Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | TYMP | P19971 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14395308 | 1.00 | NPC1 (0.50) | NPC1SMN1; SMN2RAB9ACES2CES1 | |
| SCHEMBL31080818 | 1.00 | NPC1 (0.50) | NPC1SMN1; SMN2RAB9ACES2CES1 | |
| SCHEMBL18517293 | 0.80 | NPC1 (0.49) | NPC1SMN1; SMN2RAB9ACES2CES1 | |
| SCHEMBL28127811 | 0.80 | NPC1 (0.49) | NPC1SMN1; SMN2RAB9ACES2CES1 | |
| SCHEMBL8664564 | 0.77 | CES2 (0.43) | NPC1SMN1; SMN2RAB9ACES2CES1 | |
| SCHEMBL18938849 | 0.77 | SMN1; SMN2 (0.46) | NPC1SMN1; SMN2RAB9ACES2CES1 | |
| SCHEMBL6815533 | 0.77 | SMN1; SMN2 (0.46) | NPC1SMN1; SMN2RAB9ACES2CES1 | |
| SCHEMBL8664565 | 0.77 | CES2 (0.43) | NPC1SMN1; SMN2RAB9ACES2CES1 | |
| SCHEMBL17842362 | 0.76 | CES2 (0.52) | NPC1SMN1; SMN2RAB9ACES2CES1 | |
| SCHEMBL14127160 | 0.75 | CES2 (0.56) | NPC1SMN1; SMN2RAB9ACES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230172206-A1 | USE OF STROBILURIN TYPE COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI CONTAINING AN AMINO ACID SUBSTITUTION F129L IN THE MITOCHONDRIAL CYTOCHROME B PROTEIN CONFERRING RESISTANCE TO QO INHIBITORS II | BASF SE (DE) | 2023-06-08 | — | — | US | disclosed |
| CN-115484821-A | Use of strobilurin-type compounds to control phytopathogenic fungi containing the amino acid substitution F129L in the mitochondrial cytochrome b protein conferring tolerance to Qo inhibitor III | 巴斯夫欧洲公司 | 2022-12-16 | — | — | CN | disclosed |
| CN-115484820-A | Use of strobilurin-type compounds to control phytopathogenic fungi containing in the mitochondrial cytochrome b protein an amino acid substitution F129L conferring tolerance to Qo inhibitor I | 巴斯夫欧洲公司 | 2022-12-16 | — | — | CN | disclosed |
| CN-115460920-A | Use of strobilurin-type compounds to control phytopathogenic fungi containing in the mitochondrial cytochrome b protein an amino acid substitution F129L conferring tolerance to Qo inhibitor II | 巴斯夫欧洲公司 | 2022-12-09 | — | — | CN | disclosed |
| CN-115460919-A | Use of strobilurin-type compounds to control phytopathogenic fungi containing the amino acid substitution F129L in the mitochondrial cytochrome b protein conferring tolerance to Qo inhibitors IV | 巴斯夫欧洲公司 | 2022-12-09 | — | — | CN | disclosed |
| EP-1385847-A2 | PYRAZOLO[1,5-A]PYRIDINE DERIVATIVES | SmithKline Beecham Corporation (US) | 2004-02-04 | — | — | EP | disclosed |
| WO-2002088124-A2 | PYRAZOLO'1,5-A!PYRIDINE DERIVATIVES | SMITHKLINE BEECHAM CORPORATION (US) | 2002-11-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230172206-A1 | USE OF STROBILURIN TYPE COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI CONTAINING AN AMINO ACID SUBSTITUTION F129L IN THE MITOCHONDRIAL CYTOCHROME B PROTEIN CONFERRING RESISTANCE TO QO INHIBITORS II | COX5B, SQOR, UQCRB | NPC1 1487/4885SMN1; SMN2 3370/4885RAB9A 448/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.