SCHEMBL6630644

SCHEMBL6630644

c1csc(C2CNCO2)c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.38
TSHR P16473 1/20 0.38
HTT P42858 1/20 0.38
ALDH1A1 P00352 4/20 0.37
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
MAPT P10636 5/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
HPGD P15428 3/20 0.35
ALOX15 P16050 1/20 0.35
ALOX12 P18054 1/20 0.35
HSD17B10 Q99714 1/20 0.34
ATM Q13315 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
GAA P10253 3/20 0.33
POLB P06746 1/20 0.33
DRD2 P14416 1/20 0.33
DRD3 P35462 1/20 0.33
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7010502 0.85 DRD2 (0.47) DRD2DRD3
SCHEMBL30100984 0.81 KDM4E (0.36) KDM4ETSHRHTTALDH1A1MEN1
Acetone SCHEMBL22660844 0.77 DRD2 (0.44) DRD2DRD3
SCHEMBL19354579 0.77
SCHEMBL1522730 0.77
SCHEMBL30100967 0.75 ALDH1A1 (0.40) KDM4ETSHRHTTALDH1A1MEN1
SCHEMBL19690771 0.74
SCHEMBL7475896 0.71 KDM4E (0.42) KDM4ETSHRHTTALDH1A1MEN1
SCHEMBL3648603 0.71 HTR3A (0.44) ALDH1A1MEN1KMT2AMAPTGAA
SCHEMBL2044222 0.69 SMN1; SMN2 (0.43) KDM4ETSHRHTTALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1404681-A1 PROCESS FOR THE PREPARATION OF TETRAHYDROTHIENO [3,2-C] PYRIDINE DERIVATIVES Brantford Chemicals Inc. (CA) 2004-04-07 EP disclosed
WO-2003004502-A1 PROCESS FOR THE PREPARATION OF TETRAHYDROTHIENO [3,2-C] PYRIDINE DERIVATIVES BRANTFORD CHEMICALS INC. (CA) 2003-01-16 WO disclosed
US-6495691-B1 THEIR PHARMACEUTICALLY ACCEPTABLE SALTS, WHEREIN THE MEANING OF X IS HYDROGEN, CARBOXYL, ALKOXYCARBONYL, ARYLOXYCARBONYL, NITRILE, OR CARBAMOYL OF THE FORMULA TICLOPIDINE, IS AN ANTITHROMBOTIC DRUG WITH PLATELET AGGREGATION INHIBITING BRANTFORD CHEMICALS INC. (CA) 2002-12-17 US disclosed
CN-1025141-C Herbicidal compositions containing 5-heterocycle substituted oxazolidine dihaloacetamide antidotes and uses thereof MONSANTO CO (US) 1994-06-29 CN disclosed
US-5256626-A Herbicidal compositions safened by 5-heterocyclic-substituted oxazolidine dihaloacetamides compounds MONSANTO COMPANY (US) 1993-10-26 US disclosed
US-5225570-A Plant safening agents for crops treated with herbicides MONSANTO COMPANY (US) 1993-07-06 US disclosed
EP-0304409-B1 5-HETEROCYCLIC-SUBSTITUTED OXAZOLIDINE HALOACETAMIDES MONSANTO CO (US) 1992-10-28 EP disclosed
CN-1031375-A The  oxazolidine dihaloacetamides class of 5-heterocyclic substituted MONSANTO CO (US) 1989-03-01 CN disclosed
EP-0304409-A1 5-Heterocyclic-substituted oxazolidine haloacetamides MONSANTO COMPANY (US) 1989-02-22 EP disclosed