Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.59 |
| ▸ | HPGD | P15428 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | KLK7 | P49862 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5516360 | 0.79 | ALDH1A1 (0.52) | ALDH1A1HPGDKDM4EMAPTHDAC1 | |
| SCHEMBL5054452 | 0.75 | ALDH1A1 (1.00) | ALDH1A1HPGDKDM4EMAPTHDAC1 | |
| SCHEMBL29581351 | 0.75 | ALDH1A1 (1.00) | ALDH1A1HPGDKDM4EMAPTHDAC1 | |
| SCHEMBL20726340 | 0.74 | ALDH1A1 (0.51) | ALDH1A1HPGDKDM4EMAPTHDAC1 | |
| SCHEMBL8333925 | 0.73 | ALDH1A1 (0.97) | ALDH1A1HPGDKDM4EMAPTHDAC1 | |
| SCHEMBL8333926 | 0.73 | ALDH1A1 (0.97) | ALDH1A1HPGDKDM4EMAPTHDAC1 | |
| SCHEMBL9745919 | 0.72 | ALDH1A1 (0.71) | ALDH1A1HPGDKDM4EMAPTNPC1 | |
| SCHEMBL463597 | 0.71 | ALDH1A1 (0.61) | ALDH1A1HPGDHDAC1HDAC3HDAC2 | |
| SCHEMBL29904721 | 0.71 | ALDH1A1 (0.61) | ALDH1A1HPGDHDAC1HDAC3HDAC2 | |
| SCHEMBL11787125 | 0.71 | JAK2 (0.37) | ALDH1A1HPGDKDM4EMAPTCASP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5830931-A | DYEING SYNTHETIC HYDROPHOBIC MATERIAL | BAYER AKTIENGESELLSCHAFT (DE) | 1998-11-03 | — | — | US | claimed |
| US-6833455-B2 | Coloring plastics | BAYER AKTIENGESELLSCHAFT (DE) | 2004-12-21 | — | — | US | disclosed |
| EP-1314754-B1 | Bridged Perinones/Quinophtalones | BAYER CHEMICALS AG (DE) | 2004-09-22 | — | — | EP | disclosed |
| US-20030139498-A1 | Bridged perinones/quinophthalones | BAYER AKTIENGESELLSCHAFT (DE) | 2003-07-24 | — | — | US | disclosed |
| EP-1118640-B1 | Bridged perinone, quinophthalone and perinone-quinophthalone | BAYER AG (DE) | 2003-07-23 | — | — | EP | disclosed |
| EP-1314754-A1 | Bridged Perinones/Quinophtalones | Bayer Aktiengesellschaft (DE) | 2003-05-28 | — | — | EP | disclosed |
| EP-0827986-B1 | Bridged perinone, quinophthalone and perinone-quinophthalone | BAYER AG (DE) | 2002-03-27 | — | — | EP | disclosed |
| EP-0780444-B1 | Process to manufacture polycyclic compounds | BAYER AG (DE) | 2001-09-05 | — | — | EP | disclosed |
| EP-1118640-A1 | Bridged perinone, quinophthalone and perinone-quinophthalone | BAYER AG (DE) | 2001-07-25 | — | — | EP | disclosed |
| US-5955614-A | Bridged perinones/quinophthalones | BAYER AKTIENGESELLSCHAFT (DE) | 1999-09-21 | — | — | US | disclosed |
| US-5830931-A | DYEING SYNTHETIC HYDROPHOBIC MATERIAL | BAYER AKTIENGESELLSCHAFT (DE) | 1998-11-03 | — | — | US | disclosed |
| EP-0827986-A2 | Bridged perinone, quinophthalone and perinone-quinophthalone | BAYER AG (DE) | 1998-03-11 | — | — | EP | disclosed |
| EP-0780444-A2 | Process to manufacture polycyclic compounds | BAYER AG (DE) | 1997-06-25 | — | — | EP | disclosed |
| US-5621027-A | Dyestuffs for bulk dyeing plastics | BAYER AKTIENGESELLSCHAFT (DE) | 1997-04-15 | — | — | US | disclosed |
| US-5530130-A | DYEING PLASTICS | BAYER AKTIENGESELLSCHAFT (DE) | 1996-06-25 | — | — | US | disclosed |
| EP-0683212-A1 | New dyes for the bulk dyeing of synthetic materials | BAYER AG (DE) | 1995-11-22 | — | — | EP | disclosed |
| EP-0639624-A1 | Phthaloperinone dyestuffs | BAYER AG (DE) | 1995-02-22 | — | — | EP | disclosed |
| US-4024144-A | SULFONIC ACID GROUPS | BAYER AKTIENGESELLSCHAFT (DT) | 1977-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030139498-A1 | Bridged perinones/quinophthalones | CYP11B1, CYP1B1, CYP11B2 | ALDH1A1 310/4885HPGD 553/4885KDM4E 3339/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.