Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | CMA1 | P23946 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6627585 | 0.80 | CMA1 (0.40) | KIF11CMA1 | |
| SCHEMBL6627615 | 0.77 | BCAT1 (0.48) | SMN1; SMN2 | |
| SCHEMBL7670892 | 0.75 | AR (0.31) | — | |
| SCHEMBL9476930 | 0.75 | CMA1 (0.35) | CMA1MEN1LMNATP53MAPT | |
| SCHEMBL9479017 | 0.72 | CMA1 (0.33) | CMA1MEN1LMNATP53MAPT | |
| SCHEMBL22520003 | 0.72 | BCAT2 (0.30) | — | |
| SCHEMBL9030993 | 0.71 | KARS1 (0.30) | — | |
| SCHEMBL8927953 | 0.71 | BCAT2 (0.40) | — | |
| SCHEMBL9522971 | 0.70 | SLC22A12 (0.34) | KMT2A | |
| SCHEMBL7756617 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040186021-A1 | Substituted benzo-nitro-heterocycles | BAYER CROPSCIENCE AG (DE) | 2004-09-23 | — | — | US | disclosed |
| EP-1409484-A1 | SUBSTITUTED BENZO-NITRO-HETEROCYCLES | Bayer CropScience AG (DE) | 2004-04-21 | — | — | EP | disclosed |
| WO-2003006461-A1 | SUBSTITUTED BENZO-NITRO-HETEROCYCLES | BAYER CROPSCIENCE AG (DE) | 2003-01-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040186021-A1 | Substituted benzo-nitro-heterocycles | NQO1, CBR1, MT-ND1 | KIF11 3936/4885CMA1 2983/4885MEN1 3025/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.