Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25795526 | 0.84 | KMT2A (0.44) | ATMKMT2APOLBALDH1A1HPGD | |
| SCHEMBL12604508 | 0.84 | KMT2A (0.44) | ATMKMT2APOLBALDH1A1HPGD | |
| SCHEMBL673966 | 0.84 | KMT2A (0.44) | ATMKMT2APOLBALDH1A1HPGD | |
| SCHEMBL11671625 | 0.82 | ATM (0.41) | ATMKMT2APOLBALDH1A1HPGD | |
| SCHEMBL11350774 | 0.82 | ATM (0.41) | ATMKMT2APOLBALDH1A1HPGD | |
| SCHEMBL14344759 | 0.82 | ATM (0.41) | ATMKMT2APOLBALDH1A1HPGD | |
| SCHEMBL673023 | 0.82 | POLB (0.50) | ATMKMT2APOLBALDH1A1HPGD | |
| SCHEMBL3078037 | 0.81 | ATM (0.39) | ATMKMT2APOLBALDH1A1HPGD | |
| SCHEMBL3078036 | 0.81 | ATM (0.39) | ATMKMT2APOLBALDH1A1HPGD | |
| SCHEMBL19526944 | 0.77 | KMT2A (0.38) | ATMKMT2APOLBALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8846851-B2 | Methods of ring opening polymerization and catalysts therefor | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2014-09-30 | — | — | US | claimed |
| US-20130158226-A1 | METHODS OF RING OPENING POLYMERIZATION AND CATALYSTS THEREFOR | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2013-06-20 | — | — | US | claimed |
| US-20120046437-A1 | METHODS OF RING OPENING POLYMERIZATION AND CATALYSTS THEREFOR | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2012-02-23 | — | — | US | claimed |
| US-8846851-B2 | Methods of ring opening polymerization and catalysts therefor | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2014-09-30 | — | — | US | disclosed |
| US-8541477-B2 | Methods of depolymerizing terephthalate polyesters | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2013-09-24 | — | — | US | disclosed |
| US-8507640-B2 | Methods of ring opening polymerization and catalysts therefor | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2013-08-13 | — | — | US | disclosed |
| US-20130158226-A1 | METHODS OF RING OPENING POLYMERIZATION AND CATALYSTS THEREFOR | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2013-06-20 | — | — | US | disclosed |
| WO-2012121985-A2 | METHODS OF DEPOLYMERIZING TEREPHTHALATE POLYESTERS | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2012-09-13 | — | — | WO | disclosed |
| US-20120223270-A1 | METHODS OF DEPOLYMERIZING TEREPHTHALATE POLYESTERS | KING ABDULAZIZ CITY FOR SCIENCE AND TECHNOLOGY (SA) | 2012-09-06 | — | — | US | disclosed |
| US-20120046437-A1 | METHODS OF RING OPENING POLYMERIZATION AND CATALYSTS THEREFOR | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2012-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120223270-A1 | METHODS OF DEPOLYMERIZING TEREPHTHALATE POLYESTERS | DDT, TRHDE, TERT | ATM 3056/4885KMT2A 2915/4885POLB 869/4885 |
| US-20120046437-A1 | METHODS OF RING OPENING POLYMERIZATION AND CATALYSTS THEREFOR | OGFOD1, PCNA, ODC1 | ATM 4056/4885KMT2A 3440/4885POLB 153/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.