Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | THPO | P40225 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | TTPA | P49638 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4957168 | 1.00 | PTGS2 (0.44) | PTGS2SMN1; SMN2KDM4EMAPTTHRB | |
| SCHEMBL13397045 | 0.86 | CA12 (0.36) | PTGS2CA12CA1CA2CA4 | |
| Ibuprofen SCHEMBL7573168 | 0.81 | PTGS2 (0.48) | PTGS2NFKB1BLMPTGS1 | |
| SCHEMBL3051431 | 0.80 | KDM4E (0.50) | PTGS2SMN1; SMN2KDM4EMAPTTHRB | |
| SCHEMBL3051429 | 0.80 | KDM4E (0.50) | PTGS2SMN1; SMN2KDM4EMAPTTHRB | |
| SCHEMBL4959876 | 0.80 | ITGB1 (0.37) | PTGS2SMN1; SMN2KDM4EMAPTTHRB | |
| SCHEMBL110903 | 0.79 | KDM4E (0.49) | PTGS2SMN1; SMN2KDM4EMAPTTHRB | |
| SCHEMBL3050141 | 0.79 | KDM4E (0.49) | PTGS2SMN1; SMN2KDM4EMAPTTHRB | |
| SCHEMBL7576555 | 0.79 | SMN1; SMN2 (0.49) | PTGS2SMN1; SMN2KDM4EMAPTTHRB | |
| SCHEMBL112448 | 0.79 | KDM4E (0.49) | PTGS2SMN1; SMN2KDM4EMAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1417165-A2 | DRUGS FOR CHRONIC PAINS | Nicox S.A. (FR) | 2004-05-12 | — | — | EP | claimed |
| WO-2003000642-A2 | DRUGS FOR CHRONIC PAINS | NICOX S.A. (FR) | 2003-01-03 | — | — | WO | claimed |
| WO-2002092072-A2 | DRUGS FOR THE TREATMENT OF THE ALZHEIMER DISEASE | NICOX S.A. (FR) | 2002-11-21 | — | — | WO | claimed |
| US-20040171682-A1 | Drugs for chronic pains | NICOX S.A. (FR) | 2004-09-02 | — | — | US | disclosed |
| EP-1417165-A2 | DRUGS FOR CHRONIC PAINS | Nicox S.A. (FR) | 2004-05-12 | — | — | EP | disclosed |
| WO-2003000642-A2 | DRUGS FOR CHRONIC PAINS | NICOX S.A. (FR) | 2003-01-03 | — | — | WO | disclosed |
| WO-2003000643-A1 | NITRATE ESTER DERIVATIVES USEFUL FOR PREPARING DRUGS FOR EPILEPSY | NICOX S.A. (FR) | 2003-01-03 | — | — | WO | disclosed |
| WO-2002092072-A2 | DRUGS FOR THE TREATMENT OF THE ALZHEIMER DISEASE | NICOX S.A. (FR) | 2002-11-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040171682-A1 | Drugs for chronic pains | OPRD1, OPRK1, OPRL1 | PTGS2 167/4885SMN1; SMN2 1127/4885KDM4E 4186/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.