Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 8/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPY2R | P49146 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6632031 | 0.93 | BCHE (0.37) | HSD17B10KDM4EADRB2GPR119TSHR | |
| SCHEMBL3850149 | 0.81 | HSD17B10 (0.42) | HSD17B10KDM4EADRB2GPR119TSHR | |
| SCHEMBL6633698 | 0.81 | HSD17B10 (0.38) | HSD17B10KDM4EADRB2GPR119TSHR | |
| SCHEMBL5189897 | 0.77 | HSD17B10 (0.45) | HSD17B10KDM4EADRB2TSHRALDH1A1 | |
| SCHEMBL6634428 | 0.75 | ALDH1A1 (0.33) | KDM4EALDH1A1GAAKMT2ALMNA | |
| SCHEMBL6637256 | 0.74 | NPY2R (0.38) | ALDH1A1MAPK1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL6632840 | 0.74 | TDP1 (0.32) | KDM4EALDH1A1GAA | |
| SCHEMBL3855173 | 0.74 | P2RX7 (0.39) | HSD17B10KDM4EADRB2GPR119TSHR | |
| SCHEMBL6636249 | 0.73 | APP (0.35) | — | |
| SCHEMBL6633780 | 0.73 | NCEH1 (0.32) | GAANPY2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1000051-B1 | CARBAMYLOXY COMPOUNDS WHICH INHIBIT LEUKOCYTE ADHESION MEDIATED BY VLA-4 | ELAN PHARM INC (US) | 2004-05-19 | — | — | EP | claimed |