Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 10/20 | 0.38 |
| ▸ | TSHR | P16473 | 8/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.34 |
| ▸ | LMNA | P02545 | 4/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6635754 | 0.81 | LMNA (0.37) | HSD17B10TSHRALDH1A1CYP3A4SMN1; SMN2 | |
| SCHEMBL6632073 | 0.81 | HSD17B10 (0.42) | HSD17B10TSHRALDH1A1CYP3A4SMN1; SMN2 | |
| SCHEMBL3853158 | 0.80 | P2RX7 (0.39) | HSD17B10TSHRALDH1A1CYP3A4SMN1; SMN2 | |
| SCHEMBL6632031 | 0.80 | BCHE (0.37) | HSD17B10TSHRALDH1A1CYP3A4SMN1; SMN2 | |
| SCHEMBL6636006 | 0.77 | OXTR (0.32) | ALDH1A1KMT2A | |
| SCHEMBL6637256 | 0.76 | NPY2R (0.38) | ALDH1A1CYP1A2CYP2C9CYP2C19MAPK1 | |
| SCHEMBL6636303 | 0.73 | KDM4E (0.34) | HSD17B10TSHRALDH1A1SMN1; SMN2CYP1A2 | |
| SCHEMBL3851899 | 0.70 | P2RX7 (0.38) | HSD17B10TSHRALDH1A1CYP3A4SMN1; SMN2 | |
| SCHEMBL6633881 | 0.70 | ALDH1A1 (0.42) | TSHRALDH1A1SMN1; SMN2MAPK1LMNA | |
| SCHEMBL3850149 | 0.69 | HSD17B10 (0.42) | HSD17B10TSHRALDH1A1CYP3A4SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1000051-B1 | CARBAMYLOXY COMPOUNDS WHICH INHIBIT LEUKOCYTE ADHESION MEDIATED BY VLA-4 | ELAN PHARM INC (US) | 2004-05-19 | — | — | EP | claimed |