Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | KIF11 | P52732 | 1/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.41 |
| ▸ | TUBB | P07437 | 3/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.41 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.41 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.41 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.41 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.41 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.41 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.41 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.41 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.41 |
| ▸ | TUBB6 | Q9BUF5 | 3/20 | 0.41 |
| ▸ | TUBB2B | Q9BVA1 | 3/20 | 0.41 |
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2205092 | 0.84 | HRH4 (0.56) | ALOX5KIF11HRH4MEN1KMT2A | |
| SCHEMBL2440393 | 0.80 | HRH4 (0.52) | ALOX5KIF11HRH4MEN1KMT2A | |
| SCHEMBL30310659 | 0.74 | HRH4 (0.55) | KIF11HRH4MEN1KMT2ANR4A2 | |
| SCHEMBL2134591 | 0.74 | FLT3 (0.58) | KIF11MEN1KMT2ANR4A2FLT3 | |
| SCHEMBL915460 | 0.74 | HRH4 (0.55) | KIF11HRH4MEN1KMT2ANR4A2 | |
| SCHEMBL23049701 | 0.73 | PARP1 (0.48) | ALOX5KIF11MEN1KMT2ANR4A2 | |
| SCHEMBL8655451 | 0.73 | HRH4 (0.56) | KIF11HRH4MEN1KMT2ANR4A2 | |
| SCHEMBL5568273 | 0.73 | FLT3 (0.59) | ALOX5KIF11HRH4NR4A2FLT3 | |
| SCHEMBL2323348 | 0.73 | FLT3 (0.59) | ALOX5KIF11HRH4NR4A2FLT3 | |
| SCHEMBL217459 | 0.73 | FLT3 (0.66) | HRH4MEN1KMT2AFLT3ULK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040133014-A1 | 3-Sulfenylation of indole-2-carboxylates | WALL HAMILTON HARRIET (US) | 2004-07-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040133014-A1 | 3-Sulfenylation of indole-2-carboxylates | TST, IDO2, INMT | ALOX5 2168/4885KIF11 2998/4885HRH4 1650/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.