Sugi Predict

Sugi Predict / Compounds / SCHEMBL915460

SCHEMBL915460

SCHEMBL915460

COC(=O)c1cc2c(O)cccc2[nH]1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HRH4 Q9H3N8 1/20 0.55
▸ CA12 O43570 1/20 0.50
▸ CA1 P00915 1/20 0.50
▸ CA2 P00918 1/20 0.50
▸ CA7 P43166 1/20 0.50
▸ CA9 Q16790 1/20 0.50
▸ CA14 Q9ULX7 1/20 0.50
▸ FTO Q9C0B1 1/20 0.50
▸ IDO1 P14902 2/20 0.48
▸ KIF11 P52732 1/20 0.48
▸ CYP1A2 P05177 1/20 0.47
▸ GLA P06280 1/20 0.47
▸ GAA P10253 1/20 0.47
▸ NR4A2 P43354 2/20 0.46
▸ FLT3 P36888 2/20 0.46
▸ ULK1 O75385 1/20 0.46
▸ XDH P47989 1/20 0.46
▸ KDM4E B2RXH2 2/20 0.46
▸ MEN1 O00255 1/20 0.46
▸ ALDH1A1 P00352 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30310659 1.00 HRH4 (0.55) HRH4CA12CA1CA2CA7
SCHEMBL2134591 0.84 FLT3 (0.58) IDO1KIF11CYP1A2GLAGAA
SCHEMBL913891 0.83 KDM4E (0.56) HRH4CA12CA1CA2CA7
SCHEMBL8655451 0.83 HRH4 (0.56) HRH4IDO1KIF11CYP1A2GLA
SCHEMBL2205092 0.83 HRH4 (0.56) HRH4IDO1KIF11CYP1A2GLA
SCHEMBL2323348 0.83 FLT3 (0.59) HRH4KIF11CYP1A2GLAGAA
SCHEMBL5568273 0.83 FLT3 (0.59) HRH4KIF11CYP1A2GLAGAA
SCHEMBL217459 0.83 FLT3 (0.66) HRH4IDO1GLAGAAFLT3
SCHEMBL30397530 0.81 KDM4E (0.46) FTOIDO1KIF11CYP1A2GLA
SCHEMBL20535848 0.81 KIF11 (0.46) HRH4FTOIDO1KIF11CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260116857-A1 INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOFS PARDES BIOSCIENCES INC (US) 2026-04-30 — — US disclosed
US-12145911-B2 Inhibitors of cysteine proteases and methods of use thereof Pardes Biosciences, Inc. (US) 2024-11-19 — — US disclosed
US-20240270693-A1 INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOF Pardes Biosciences, Inc. (US) 2024-08-15 — — US disclosed
US-11952365-B2 Anti-viral compounds ALIGOS THERAPEUTICS, INC. (US) 2024-04-09 — — US disclosed
CN-116685576-A Cysteine protease inhibitors and methods of use thereof 美商帕迪斯生物科学公司 2023-09-01 — — CN disclosed
US-20230212152-A1 INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOF Pardes Biosciences, Inc. 2023-07-06 — — US disclosed
US-20230212152-A1 INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOF Pardes Biosciences, Inc. 2023-07-06 — — US disclosed
US-20230212152-A1 INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOF Pardes Biosciences, Inc. 2023-07-06 — — US disclosed
CN-116096714-A Antiviral compounds for the treatment of coronavirus, picornavirus and norovirus infections 安力高医药股份有限公司 2023-05-09 — — CN disclosed
WO-2023065667-A1 NOVEL DEUTERATED BENZOTHIAZOLE COMPOUND AND PREPARATION METHOD THEREFOR AND COMPOSITION AND APPLICATION THEREOF 广州谷森制药有限公司 2023-04-27 — — WO disclosed
US-6288103-B1 MONOCYTE CHEMOATTRACTANT PROTEINS ANTAGONIST SUCH AS N-(3-CHLOROPHENYLSULPHONYL)INDOLE-2-CARBOXYLIC ACID; ANTIINFLAMMATORY AGENTS ZENECA LIMITED (GB) 2001-09-11 — — US disclosed
CN-1265591-A Coumpound ZENECA LTD (GB) 2000-09-06 — — CN disclosed
CN-1265649-A Indole derivatives as MCP-1 receptor antagonists ZENECA LTD (GB) 2000-09-06 — — CN disclosed
WO-2000046198-A1 ANTI-INFLAMMATORY INDOLE DERIVATIVES ASTRAZENECA AB (SE) 2000-08-10 — — WO disclosed
EP-1003504-A2 INDOLE DERIVATIVES AND THEIR USE AS MCP-1 ANTAGONISTS AstraZeneca UK Limited (GB) 2000-05-31 — — EP disclosed
EP-1001935-A1 INDOLE DERIVATIVES AS MCP-1 RECEPTOR ANTAGONISTS ZENECA LIMITED (GB) 2000-05-24 — — EP disclosed
WO-1999007351-A2 INDOLE DERIVATIVES AND THEIR USE AS MCP-1 ANTAGONISTS ZENECA LIMITED (GB) 1999-02-18 — — WO disclosed
WO-1999007678-A1 INDOLE DERIVATIVES AS MCP-1 RECEPTOR ANTAGONISTS ZENECA LIMITED (GB) 1999-02-18 — — WO disclosed
EP-0234946-A2 New compounds THE WELLCOME FOUNDATION LIMITED (GB) 1987-09-02 — — EP disclosed
EP-0174162-A2 Pharmaceutically active dipeptide derivatives THE WELLCOME FOUNDATION LIMITED (GB) 1986-03-12 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11952365-B2 Anti-viral compounds EIF2AK2, ZC3HAV1, HAVCR2 HRH4 3391/4885CA12 2699/4885CA1 4151/4885
US-20260116857-A1 INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOFS CTRC, CTRL, CTSL HRH4 1110/4885CA12 371/4885CA1 213/4885
US-20240270693-A1 INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOF CTRL, CTSV, CTSL HRH4 4013/4885CA12 703/4885CA1 651/4885
US-12145911-B2 Inhibitors of cysteine proteases and methods of use thereof CTRL, CTSV, CTSL HRH4 4013/4885CA12 703/4885CA1 651/4885
US-20230212152-A1 INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOF CTRL, CTSL, CTSV HRH4 4259/4885CA12 410/4885CA1 545/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.