Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11352364 | 0.82 | L3MBTL1 (0.55) | L3MBTL1MEN1KMT2ALMNAHTT | |
| SCHEMBL27427330 | 0.74 | SMN1; SMN2 (0.63) | MEN1KMT2ALMNANPC1HTT | |
| SCHEMBL5651149 | 0.74 | L3MBTL1 (0.47) | L3MBTL1MEN1KMT2ALMNANPC1 | |
| SCHEMBL59717 | 0.74 | RAB9A (0.55) | MEN1KMT2ANPC1HTTALDH1A1 | |
| SCHEMBL56875 | 0.73 | L3MBTL1 (0.73) | L3MBTL1MEN1KMT2ALMNAHTT | |
| SCHEMBL29475389 | 0.73 | L3MBTL1 (0.73) | L3MBTL1MEN1KMT2ALMNAHTT | |
| SCHEMBL6630173 | 0.72 | KDM4E (0.64) | L3MBTL1NPC1HTTALDH1A1SMN1; SMN2 | |
| SCHEMBL423891 | 0.72 | L3MBTL1 (0.71) | L3MBTL1MEN1KMT2ALMNANPC1 | |
| SCHEMBL17787233 | 0.71 | L3MBTL1 (0.59) | L3MBTL1MEN1KMT2ALMNAHTT | |
| SCHEMBL5391424 | 0.71 | L3MBTL1 (0.59) | L3MBTL1MEN1KMT2ALMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1458374-A2 | COMPOUNDS AND USES THEREOF FOR DECREASING ACTIVITY OF HORMONE-SENSITIVE LIPASE | NOVO NORDISK A/S (DK) | 2004-09-22 | — | — | EP | disclosed |
| WO-2003051841-A2 | COMPOUNDS AND USES THEREOF FOR DECREASING ACTIVITY OF HORMONE-SENSITIVE LIPASE | NOVO NORDISK A/S (DK) | 2003-06-26 | — | — | WO | disclosed |