Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | EDNRB | P24530 | 1/20 | 0.36 |
| ▸ | EDNRA | P25101 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.36 |
| ▸ | RELA | Q04206 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | FLT3 | P36888 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27916062 | 0.91 | ALDH1A1 (0.35) | HPGDALDH1A1MAPTLMNA | |
| SCHEMBL6632251 | 0.83 | MAPT (0.43) | MEN1KMT2AEDNRBEDNRANPC1 | |
| Hydrochloric Acid SCHEMBL6927081 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL6923403 | 0.75 | — | — | |
| SCHEMBL7926988 | 0.75 | DRD2 (0.31) | — | |
| SCHEMBL28814695 | 0.72 | GPR3 (0.36) | MEN1KMT2APOLBLMNA | |
| SCHEMBL6569636 | 0.71 | ALDH1A1 (0.40) | KMT2ANPC1RAB9ATDP1ALDH1A1 | |
| SCHEMBL7028244 | 0.70 | CHRNB2 (0.33) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL16321982 | 0.70 | CHRNB2 (0.33) | — | |
| SCHEMBL7026733 | 0.70 | CHRNB2 (0.33) | MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1033130-B1 | INHIBITOR OF UROKINASE PRODUCTION AND OF ANGIOGENESIS AND ITS THERAPEUTIC USE | TAIHO PHARMACEUTICAL CO LTD (JP) | 2004-04-21 | — | — | EP | disclosed |
| US-6365610-B1 | 1,4-EPOXY-2,3-BENZODIOXEPINS OR 1,4-EPOXY-3,2-BENZOXAZEPINES | TAIHO PHARMACEUTICAL COMPANY LTD. (JP) | 2002-04-02 | — | — | US | disclosed |
| EP-1033130-A1 | UROKINASE PRODUCTION INHIBITORS, ANGIOGENESIS INHIBITORS AND METHODS OF PREVENTION OR TREATMENT WITH BOTH | TAIHO PHARMACEUTICAL COMPANY LIMITED (JP) | 2000-09-06 | — | — | EP | disclosed |