SCHEMBL6633461

SCHEMBL6633461

CCCCCCCCCCCCCCCCCC(=O)NNC(=O)c1ccccc1O

nearest known ligand 0.62

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 1/20 0.62
MEN1 O00255 1/20 0.58
KMT2A Q03164 1/20 0.58
POLB P06746 1/20 0.58
GAA P10253 1/20 0.56
CA1 P00915 1/20 0.54
CA9 Q16790 1/20 0.54
L3MBTL1 Q9Y468 1/20 0.53
GSK3B P49841 4/20 0.53
P2RX7 Q99572 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11315978 1.00 NAAA (0.62) NAAAMEN1KMT2APOLBGAA
SCHEMBL13990402 1.00 NAAA (0.62) NAAAMEN1KMT2APOLBGAA
SCHEMBL1169074 0.92 L3MBTL1 (0.59) NAAAPOLBGAACA1CA9
SCHEMBL29417865 0.92 L3MBTL1 (0.59) NAAAPOLBGAACA1CA9
SCHEMBL30912997 0.91 L3MBTL1 (0.61) POLBGAACA1CA9L3MBTL1
SCHEMBL6635022 0.88 CA1 (0.59) NAAAGAACA1CA9L3MBTL1
SCHEMBL13593272 0.87 L3MBTL1 (0.54) MEN1KMT2APOLBCA1CA9
SCHEMBL8627299 0.84 LMNA (0.64) NAAAMEN1KMT2APOLBGAA
SCHEMBL8628195 0.84 LMNA (0.64) NAAAMEN1KMT2APOLBGAA
SCHEMBL8387971 0.84 LMNA (0.64) NAAAMEN1KMT2APOLBGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1420044-A2 Rubber composition and pneumatic tire Bridgestone Corporation (JP) 2004-05-19 EP disclosed
US-6380288-B1 LOW HEAT GENERATION PROPERTY, AGING REISTANCE, ALSO FOR PRODUCING VIBRATION ISOLATORS, BELTS AND HOSES AS WELL AS TIRE MATERIALS SUCH AS TIRE TREADS, UNDERTREADS, CARCASSES, SIDE WALLS AND BEADS BRIDGESTONE CORPORATION 2002-04-30 US disclosed
EP-0909788-A1 RUBBER COMPOSITION AND PNEUMATIC TIRES Bridgestone Corporation (JP) 1999-04-21 EP disclosed
US-4306930-A INCORPORATING A HYDRAZIDE OR DIHYDRAZIDE AND THEN VULCANIZING IN CONTACT WITH A METAL CIBA-GEIGY CORPORATION (US) 1981-12-22 US disclosed
US-4077948-A N-SALICYLIDENE-N*-SALICYLHYDRAZIDES CIBA-GEIGY CORPORATION (US) 1978-03-07 US disclosed
US-4052362-A N-CINNAMOYL-N'-ACYLHYDRAZINES UBE INDUSTRIES, LTD. (JA) 1977-10-04 US disclosed
US-4043976-A N,N'-DIBENZOYLHYDRAZINE DERIVATIVE UBE INDUSTRIES, LTD. (JA) 1977-08-23 US disclosed
US-3994987-A Metal deactivators as adhesion promotors for vulcanizable elastomers to metals CIBA-GEIGY CORPORATION (US) 1976-11-30 US disclosed