Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 5/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | MMP7 | P09237 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | CCR5 | P51681 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
| ▸ | NPY2R | P49146 | 2/20 | 0.34 |
| ▸ | BCL9 | O00512 | 1/20 | 0.34 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | STAT5B | P51692 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PTGES | O14684 | 1/20 | 0.33 |
| ▸ | STAT3 | P40763 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3850286 | 0.81 | P2RX7 (0.43) | P2RX7MMP1MMP3MMP7MMP9 | |
| SCHEMBL6636214 | 0.80 | ALDH1A1 (0.34) | ALDH1A1MEN1LMNAKMT2APTGES | |
| SCHEMBL4413833 | 0.78 | P2RX7 (0.45) | P2RX7MMP1MMP3MMP7MMP9 | |
| SCHEMBL6633734 | 0.78 | ALDH1A1 (0.33) | ALDH1A1MEN1KMT2APTGES | |
| SCHEMBL6664426 | 0.78 | ALDH1A1 (0.33) | ALDH1A1MEN1LMNAKMT2APTGES | |
| SCHEMBL8060247 | 0.76 | P2RX7 (0.39) | P2RX7MMP1MMP3MMP7MMP9 | |
| SCHEMBL6660613 | 0.73 | NPY2R (0.35) | MMP13GPR119NPY2RALDH1A1MEN1 | |
| SCHEMBL6633816 | 0.73 | ALDH1A1 (0.38) | NPY2RALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL6659012 | 0.72 | NPY2R (0.35) | MMP13GPR119NPY2RALDH1A1MEN1 | |
| SCHEMBL6666784 | 0.72 | POLB (0.32) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1000051-B1 | CARBAMYLOXY COMPOUNDS WHICH INHIBIT LEUKOCYTE ADHESION MEDIATED BY VLA-4 | ELAN PHARM INC (US) | 2004-05-19 | — | — | EP | claimed |