Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | PTGES | O14684 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.31 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.31 |
| ▸ | NPY2R | P49146 | 1/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6636214 | 0.91 | ALDH1A1 (0.34) | ALDH1A1PTGESMAPTKDM4EHSP90AA1 | |
| SCHEMBL6638193 | 0.86 | ALDH1A1 (0.36) | ALDH1A1PTGESMAPTKDM4EHSP90AA1 | |
| SCHEMBL6636510 | 0.83 | ALDH1A1 (0.37) | ALDH1A1PTGESMAPTKDM4EHSP90AA1 | |
| SCHEMBL6666837 | 0.78 | RAB9A (0.36) | ALDH1A1MAPTRAB9AMEN1KMT2A | |
| SCHEMBL6633703 | 0.78 | ALDH1A1 (0.37) | ALDH1A1PTGESMAPTKDM4EHSP90AA1 | |
| SCHEMBL6631786 | 0.78 | ALDH1A1 (0.32) | ALDH1A1PTGES | |
| SCHEMBL6664426 | 0.77 | ALDH1A1 (0.33) | ALDH1A1PTGESMAPTKDM4EHSP90AA1 | |
| SCHEMBL6633734 | 0.77 | ALDH1A1 (0.33) | ALDH1A1PTGESMAPTKDM4EHSP90AA1 | |
| SCHEMBL6631913 | 0.76 | ALDH1A1 (0.33) | ALDH1A1PTGESMAPTKDM4EHSP90AA1 | |
| SCHEMBL6631970 | 0.75 | TDP1 (0.35) | ALDH1A1MAPTKDM4ERAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1000051-B1 | CARBAMYLOXY COMPOUNDS WHICH INHIBIT LEUKOCYTE ADHESION MEDIATED BY VLA-4 | ELAN PHARM INC (US) | 2004-05-19 | — | — | EP | claimed |