Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.30 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.30 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6633406 | 0.94 | — | — | |
| SCHEMBL6633373 | 0.91 | HSD11B1 (0.33) | HSD11B1BCHEACHE | |
| SCHEMBL6634560 | 0.91 | PGR (0.34) | PGRNR1H2NR1H3BCHEACHE | |
| SCHEMBL6631926 | 0.91 | USP2 (0.33) | ACHEMEN1KMT2A | |
| SCHEMBL6633579 | 0.89 | HSD11B1 (0.32) | HSD11B1 | |
| SCHEMBL6634581 | 0.88 | — | — | |
| SCHEMBL6636818 | 0.88 | PGR (0.33) | PGRHSD11B1 | |
| SCHEMBL6635534 | 0.88 | ALDH1A1 (0.33) | MEN1KMT2A | |
| SCHEMBL6635177 | 0.88 | USP2 (0.32) | BCHEACHE | |
| SCHEMBL6634608 | 0.87 | KMT2A (0.34) | BCHEACHEMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1000051-B1 | CARBAMYLOXY COMPOUNDS WHICH INHIBIT LEUKOCYTE ADHESION MEDIATED BY VLA-4 | ELAN PHARM INC (US) | 2004-05-19 | — | — | EP | claimed |