Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 3/20 | 0.43 |
| ▸ | AR | P10275 | 2/20 | 0.42 |
| ▸ | HTR2B | P41595 | 2/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.41 |
| ▸ | TUBB | P07437 | 1/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.41 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.41 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.41 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.41 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.41 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.41 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.41 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.41 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.41 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6415389 | 0.73 | HTR2C (0.52) | MAPTMEN1KMT2AL3MBTL1HTR2C | |
| SCHEMBL6408330 | 0.72 | HTR2C (0.68) | MAPTMEN1KMT2AL3MBTL1HTR2C | |
| SCHEMBL6629424 | 0.68 | HTR7 (0.43) | KMT2AHTR2CHTR2BPOLBHSD11B1 | |
| SCHEMBL6629235 | 0.65 | MAPT (0.55) | MAPTMEN1KMT2AL3MBTL1LMNA | |
| SCHEMBL16918772 | 0.64 | TUBB4A (0.57) | MAPTMEN1KMT2AL3MBTL1AR | |
| SCHEMBL366147 | 0.64 | TSHR (0.54) | MAPTMEN1KMT2ATUBB4ATUBB | |
| SCHEMBL11098467 | 0.63 | PDE4D (0.64) | MAPTMEN1KMT2AL3MBTL1AR | |
| SCHEMBL13678047 | 0.63 | PDE4A (0.62) | MAPTMEN1KMT2AL3MBTL1TP53 | |
| Formaldehyde SCHEMBL27542295 | 0.63 | ALDH1A1 (0.52) | MAPTTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL845936 | 0.63 | AR (0.61) | MEN1KMT2AARGAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1465630-A1 | CYCLIC UREA DERIVATIVES WITH 5-HT2C RECEPTOR ACTIVITY | GLAXO GROUP LIMITED (GB) | 2004-10-13 | — | — | EP | disclosed |
| WO-2003057220-A1 | CYCLIC UREA DERIVATIVES WITH 5-HT2C RECEPTOR ACTIVITY | GLAXO GROUP LIMITED (GB) | 2003-07-17 | — | — | WO | disclosed |