Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 15/20 | 0.58 |
| ▸ | ADORA1 | P30542 | 12/20 | 0.58 |
| ▸ | ADORA2B | P29275 | 10/20 | 0.57 |
| ▸ | ADORA3 | P0DMS8 | 9/20 | 0.57 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.56 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.56 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6631565 | 0.94 | ADRA2A (0.57) | ADORA2AADORA1ADORA2BADORA3ADRA2A | |
| SCHEMBL6632665 | 0.90 | ADORA2A (0.63) | ADORA2AADORA1ADORA2BADORA3ADRA2A | |
| SCHEMBL6623375 | 0.85 | ADRA2A (0.67) | ADORA2AADORA1ADORA2BADORA3ADRA2A | |
| SCHEMBL6635624 | 0.85 | ADORA2A (0.63) | ADORA2A | |
| SCHEMBL6622066 | 0.85 | ADORA2A (0.61) | ADORA2AADORA1ADRA2AADRA2BADRA2C | |
| SCHEMBL6633439 | 0.83 | ADRA2A (0.56) | ADORA2AADORA1ADORA2BADORA3ADRA2A | |
| SCHEMBL6631136 | 0.83 | ADORA2A (0.56) | ADORA2AADORA1ADORA2BADORA3ADRA2A | |
| SCHEMBL6635768 | 0.83 | ADRA2A (0.57) | ADORA2AADORA1ADORA2BADORA3ADRA2A | |
| SCHEMBL6635084 | 0.83 | ADRA2A (0.59) | ADORA2AADORA1ADRA2AADRA2BADRA2C | |
| SCHEMBL6632330 | 0.82 | ADRA2A (0.71) | ADORA2AADORA1ADORA2BADORA3ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1430898-A1 | RECEPTOR ANTAGONIST | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2004-06-23 | — | — | EP | disclosed |
| US-20040110826-A1 | Receptor Antagonists | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2004-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040110826-A1 | Receptor Antagonists | ADRA2C, OPRL1, ADRB1 | ADORA2A 89/4885ADORA1 129/4885ADORA2B 170/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.