Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | CDK4 | P11802 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | CCND1 | P24385 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6644024 | 0.88 | TRPM5 (0.45) | MEN1KMT2AALDH1A1USP2CDK4 | |
| SCHEMBL6801884 | 0.79 | ROCK1 (0.47) | MEN1KMT2AALDH1A1L3MBTL1KDM4E | |
| SCHEMBL6803901 | 0.79 | ALDH1A1 (0.47) | MEN1KMT2AALDH1A1MAPTL3MBTL1 | |
| SCHEMBL6645887 | 0.77 | ALDH1A1 (0.50) | MEN1KMT2AALDH1A1USP2CDK4 | |
| SCHEMBL6639906 | 0.77 | MAPT (0.60) | MEN1KMT2AALDH1A1MAPTL3MBTL1 | |
| SCHEMBL29374038 | 0.75 | ALDH1A1 (0.62) | MEN1KMT2AALDH1A1USP2CDK4 | |
| SCHEMBL12479916 | 0.75 | ALDH1A1 (0.54) | MEN1KMT2AALDH1A1USP2CDK4 | |
| SCHEMBL11358481 | 0.73 | MAPT (0.55) | MEN1KMT2AALDH1A1USP2CDK4 | |
| SCHEMBL15972100 | 0.71 | ALDH1A1 (0.57) | MEN1KMT2AALDH1A1MAPTPOLB | |
| SCHEMBL10233859 | 0.71 | KCNJ1 (0.64) | ALDH1A1MAPTL3MBTL1KDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1383760-A1 | BIARYLCARBOXAMIDE COMPOUNDS AS APOLIPOPROTEIN B INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-01-28 | — | — | EP | disclosed |
| WO-2002090347-A1 | AMIDE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-14 | — | — | WO | disclosed |