Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.50 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CDK4 | P11802 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | CCND1 | P24385 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.48 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8177410 | 0.83 | DRD2 (0.49) | MAPTALDH1A1DRD2 | |
| SCHEMBL2769306 | 0.83 | CASP1 (0.51) | MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL20776931 | 0.82 | TSHR (0.49) | MAPTSMN1; SMN2MEN1KMT2AUSP2 | |
| SCHEMBL3149701 | 0.81 | KDM4E (0.63) | MAPTSMN1; SMN2KDM4ESIGMAR1MEN1 | |
| SCHEMBL6644024 | 0.80 | TRPM5 (0.45) | MAPTSMN1; SMN2KDM4EMEN1KMT2A | |
| SCHEMBL29558 | 0.80 | ALDH1A1 (0.66) | MAPTKDM4EMEN1KMT2AUSP2 | |
| SCHEMBL29875634 | 0.80 | ALDH1A1 (0.66) | MAPTKDM4EMEN1KMT2AUSP2 | |
| SCHEMBL15524915 | 0.79 | DRD4 (0.53) | MAPTSMN1; SMN2KDM4ESIRT2ALDH1A1 | |
| SCHEMBL5782563 | 0.79 | ALOX5 (0.50) | KMT2AALDH1A1HDAC1HDAC6 | |
| SCHEMBL28567500 | 0.79 | DRD4 (0.61) | MAPTKDM4ESIGMAR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4251659-A | Polyfluorohydroxyisopropyl-heterocyclic compounds | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-02-17 | — | — | US | disclosed |