Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6801884 | 0.91 | ROCK1 (0.47) | ALDH1A1RAB9ANPC1MAPK1POLB | |
| SCHEMBL6806299 | 0.88 | ALDH1A1 (0.49) | ALDH1A1RAB9ANPC1MAPK1MAPT | |
| SCHEMBL6493156 | 0.81 | GRIN1 (0.49) | ALDH1A1MAPK1MAPTPOLBGRIN1 | |
| SCHEMBL6636318 | 0.80 | HRH1 (0.43) | ALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL6635124 | 0.79 | MEN1 (0.49) | ALDH1A1RAB9ANPC1MAPTPOLB | |
| SCHEMBL29374038 | 0.79 | ALDH1A1 (0.62) | ALDH1A1RAB9ANPC1MAPTPOLB | |
| SCHEMBL6501814 | 0.78 | HTR2C (0.53) | ALDH1A1RAB9ANPC1MAPTPOLB | |
| SCHEMBL30376197 | 0.77 | PARP10 (0.43) | ALDH1A1MAPTPOLBKDM4EMEN1 | |
| SCHEMBL27476416 | 0.77 | MAPT (0.48) | ALDH1A1RAB9ANPC1MAPK1MAPT | |
| SCHEMBL5678082 | 0.76 | LMNA (0.53) | ALDH1A1RAB9ANPC1MAPK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040157866-A1 | Amide compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040157866-A1 | Amide compounds | APOB, NR1H2, NR1H3 | ALDH1A1 2901/4885RAB9A 4004/4885NPC1 40/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.