Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 1/20 | 0.62 |
| ▸ | MMP3 | P08254 | 1/20 | 0.59 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.50 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.50 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6636056 | 0.84 | HDAC3 (0.65) | PLK1MMP3HDAC8MEN1KMT2A | |
| SCHEMBL6635701 | 0.84 | MMP3 (0.74) | PLK1MMP3HDAC8MEN1KMT2A | |
| SCHEMBL2117675 | 0.83 | PLK1 (0.66) | PLK1MMP3HDAC8MEN1KMT2A | |
| SCHEMBL6634290 | 0.83 | PLK1 (0.57) | PLK1MMP3HDAC8MEN1KMT2A | |
| SCHEMBL6637930 | 0.82 | HDAC1 (0.58) | PLK1MMP3HDAC8MEN1KMT2A | |
| SCHEMBL15126359 | 0.81 | PLK1 (0.73) | PLK1MMP3HDAC8MEN1KMT2A | |
| SCHEMBL6639442 | 0.81 | ALDH1A1 (0.58) | PLK1MMP3HDAC8MEN1KMT2A | |
| SCHEMBL9495226 | 0.80 | PLK1 (0.54) | PLK1MMP3HDAC8MEN1KMT2A | |
| SCHEMBL6639039 | 0.77 | CA1 (0.64) | MEN1KMT2ASMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL145153 | 0.77 | HDAC8 (0.69) | PLK1MMP3HDAC8MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1420044-A2 | Rubber composition and pneumatic tire | Bridgestone Corporation (JP) | 2004-05-19 | — | — | EP | disclosed |
| US-6380288-B1 | LOW HEAT GENERATION PROPERTY, AGING REISTANCE, ALSO FOR PRODUCING VIBRATION ISOLATORS, BELTS AND HOSES AS WELL AS TIRE MATERIALS SUCH AS TIRE TREADS, UNDERTREADS, CARCASSES, SIDE WALLS AND BEADS | BRIDGESTONE CORPORATION | 2002-04-30 | — | — | US | disclosed |
| EP-0909788-A1 | RUBBER COMPOSITION AND PNEUMATIC TIRES | Bridgestone Corporation (JP) | 1999-04-21 | — | — | EP | disclosed |