Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 3/20 | 0.44 |
| ▸ | FYN | P06241 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15522393 | 0.87 | AR (0.51) | ARFYNTP53MAPK1RAB9A | |
| SCHEMBL28337685 | 0.86 | KDM4E (0.51) | ARFYNTP53MAPK1RAB9A | |
| SCHEMBL5310309 | 0.86 | KDM4E (0.51) | ARFYNTP53MAPK1RAB9A | |
| SCHEMBL1046904 | 0.86 | KDM4E (0.51) | ARFYNTP53MAPK1RAB9A | |
| SCHEMBL9206767 | 0.84 | KDM4E (0.49) | ARFYNTP53MAPK1RAB9A | |
| SCHEMBL9213633 | 0.81 | ADRB2 (0.48) | ARFYNTP53MAPK1RAB9A | |
| SCHEMBL8083196 | 0.80 | KMT2A (0.46) | ARTP53KDM4EPTGDR2LMNA | |
| SCHEMBL8631711 | 0.79 | POLB (0.47) | ARFYNKDM4EPTGDR2HDAC1 | |
| SCHEMBL8939333 | 0.78 | KDM4E (0.48) | TP53KDM4EPTGDR2LMNAHDAC1 | |
| SCHEMBL12958318 | 0.77 | IDO1 (0.48) | ARFYNTP53MAPK1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1440974-A2 | Alkylenedioxythiophenes and Poly(alkylendioxythiophenes) with mesogenic groups | Bayer Chemicals AG (DE) | 2004-07-28 | — | — | EP | disclosed |