Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.63 |
| ▸ | MAPT | P10636 | 7/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.63 |
| ▸ | RAB9A | P51151 | 4/20 | 0.63 |
| ▸ | NPC1 | O15118 | 3/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 3/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | EIF2AK3 | Q9NZJ5 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10574888 | 0.92 | GAA (0.64) | ALDH1A1MAPTSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL6638802 | 0.85 | EIF2AK3 (0.52) | ALDH1A1MAPTSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL6492613 | 0.85 | EIF2AK3 (0.59) | ALDH1A1MAPTSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL4523961 | 0.85 | HTR2C (0.58) | ALDH1A1MAPTSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL4525150 | 0.82 | EIF2AK3 (0.59) | ALDH1A1MAPTSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL4631515 | 0.82 | MAPT (0.59) | ALDH1A1MAPTSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL6501814 | 0.81 | HTR2C (0.53) | ALDH1A1MAPTSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL6804000 | 0.81 | DRD2 (0.52) | ALDH1A1MAPTSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL16989965 | 0.79 | ALDH1A1 (0.58) | ALDH1A1MAPTSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL16989951 | 0.79 | ALDH1A1 (0.58) | ALDH1A1MAPTSMN1; SMN2RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040157866-A1 | Amide compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-08-12 | — | — | US | disclosed |
| EP-1383760-A1 | BIARYLCARBOXAMIDE COMPOUNDS AS APOLIPOPROTEIN B INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-01-28 | — | — | EP | disclosed |
| WO-2002090347-A1 | AMIDE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040157866-A1 | Amide compounds | APOB, NR1H2, NR1H3 | ALDH1A1 2901/4885MAPT 4047/4885SMN1; SMN2 1854/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.