Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | EIF2AK3 | Q9NZJ5 | 1/20 | 0.45 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 2/20 | 0.45 |
| ▸ | HTR1D | P28221 | 2/20 | 0.45 |
| ▸ | HTR1B | P28222 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6501814 | 0.91 | HTR2C (0.53) | MAPTSMN1; SMN2ALDH1A1L3MBTL1EIF2AK3 | |
| SCHEMBL6638802 | 0.82 | EIF2AK3 (0.52) | MAPTSMN1; SMN2ALDH1A1L3MBTL1EIF2AK3 | |
| SCHEMBL6635461 | 0.81 | ALDH1A1 (0.63) | MAPTSMN1; SMN2ALDH1A1L3MBTL1EIF2AK3 | |
| SCHEMBL6639906 | 0.80 | MAPT (0.60) | MAPTSMN1; SMN2ALDH1A1L3MBTL1NPC1 | |
| SCHEMBL6801884 | 0.78 | ROCK1 (0.47) | ALDH1A1L3MBTL1ROCK1NPC1KMT2A | |
| SCHEMBL30912017 | 0.78 | DRD2 (0.64) | DRD2MAPTSMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL21712168 | 0.78 | DRD2 (0.64) | DRD2MAPTSMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL29191135 | 0.77 | TLR7 (0.57) | DRD2MAPTSMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL6666818 | 0.77 | SMO (0.45) | MAPTALDH1A1L3MBTL1EIF2AK3NPC1 | |
| SCHEMBL6666114 | 0.76 | SMO (0.47) | MAPTSMN1; SMN2ALDH1A1EIF2AK3NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040157866-A1 | Amide compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040157866-A1 | Amide compounds | APOB, NR1H2, NR1H3 | DRD2 3279/4885MAPT 4047/4885SMN1; SMN2 1854/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.