SCHEMBL6635490

SCHEMBL6635490

FC(F)(Br)C(F)(F)Oc1cccc(OC(F)(F)C(F)(F)Br)c1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 2/20 0.35
ALDH1A1 P00352 2/20 0.33
GAA P10253 2/20 0.33
MAPT P10636 2/20 0.33
HPGD P15428 1/20 0.33
ALOX15 P16050 1/20 0.33
TSHR P16473 1/20 0.33
HTT P42858 1/20 0.33
CETP P11597 1/20 0.33
GPR3 P46089 2/20 0.32
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
MITF O75030 1/20 0.32
GFER P55789 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
NLRP1 Q9C000 1/20 0.32
NOD2 Q9HC29 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA9 Q16790 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9169333 0.88 PIM1 (0.42) MAPTCETPSMN1; SMN2PIM1PIM2
SCHEMBL4875079 0.87 MAOB (0.43) ALDH1A1GAAMAPTHTTKMT2A
SCHEMBL9315355 0.86 ALDH1A1 (0.48) KIF11ALDH1A1GAAMAPTTSHR
SCHEMBL6468423 0.83 LTA4H (0.39) KIF11ALDH1A1ALOX15TSHRGRIN2B
SCHEMBL5320487 0.80 AKR1C3 (0.54) GAAMEN1KMT2AMITF
SCHEMBL3147185 0.77 GPR3 (0.50) KIF11CETPGPR3CHRM2CHRM1
SCHEMBL5328114 0.76 MRGPRX4 (0.51) ALDH1A1HPGDTSHRMEN1KMT2A
SCHEMBL3146332 0.74 GPR3 (0.44) KIF11ALDH1A1GAAMAPTHPGD
SCHEMBL11720083 0.74 MAOB (0.43) ALDH1A1GAAMAPTHTTKMT2A
SCHEMBL9314125 0.74 TDP1 (0.38) ALDH1A1GAAMAPTHPGDCETP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1286961-B1 SULFONATED PERFLUOROVINYL FUNCTIONAL MONOMERS 3M INNOVATIVE PROPERTIES CO (US) 2004-05-19 EP disclosed
EP-1286961-A1 SULFONATED PERFLUOROVINYL FUNCTIONAL MONOMERS 3M Innovative Properties Company (US) 2003-03-05 EP disclosed
US-6384167-B2 MECHANICAL PROPERTIES ALONG WITH A DESIRABLE LEVEL OF IONIC CONDUCTIVITY; ION-EXCHANGE MEMBRANES 3M INNOVATIVE PROPERTIES COMPANY 2002-05-07 US disclosed
US-20020007083-A1 Sulfonated perfluorovinyl functional monomers 3M INNOVATIVE PROPERTIES COMPANY 2002-01-17 US disclosed
WO-2001094305-A1 SULFONATED PERFLUOROVINYL FUNCTIONAL MONOMERS 3M INNOVATIVE PROPERTIES COMPANY (US) 2001-12-13 WO disclosed
US-6268532-B1 USED FOR PREPARING SULFONATED OR NON-SULFONATED BLOCK POLYMERS 3M INNOVATIVE PROPERTIES COMPANY 2001-07-31 US disclosed
EP-0428709-B1 REACTIVE COMPOUNDS CONTAINING PERFLUOROVINYL GROUPS DOW CHEMICAL CO (US) 1995-05-24 EP disclosed
EP-0428706-B1 PERFLUOROVINYL COMPOUNDS DOW CHEMICAL CO (US) 1994-07-13 EP disclosed
US-5198513-A Compounds for engineering thermoplastics or dimers THE DOW CHEMICAL COMPANY (US) 1993-03-30 US disclosed
US-5162468-A Polymers containing perfluorocyclobutane rings THE DOW CHEMICAL COMPANY (US) 1992-11-10 US disclosed
US-5037919-A Endcapper for polyesters, polycarbonates, polyamides and polyethers THE DOW CHEMICAL COMPANY (US) 1991-08-06 US disclosed
US-5023380-A Monomer for thermoplastic resin THE DOW CHEMICAL COMPANY (US) 1991-06-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020007083-A1 Sulfonated perfluorovinyl functional monomers AFF2, AFF1, FOS KIF11 1645/4885ALDH1A1 1362/4885GAA 4880/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.