Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 6/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.46 |
| ▸ | CD44 | P16070 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | DRD3 | P35462 | 2/20 | 0.43 |
| ▸ | ADCY6 | O43306 | 1/20 | 0.40 |
| ▸ | ADCY3 | O60266 | 1/20 | 0.40 |
| ▸ | ADCY9 | O60503 | 1/20 | 0.40 |
| ▸ | ADCY5 | O95622 | 1/20 | 0.40 |
| ▸ | ADCY8 | P40145 | 1/20 | 0.40 |
| ▸ | ADCY7 | P51828 | 1/20 | 0.40 |
| ▸ | ADCY2 | Q08462 | 1/20 | 0.40 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.40 |
| ▸ | ADCY4 | Q8NFM4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL265187 | 0.79 | KDM4E (0.49) | PNMTADRA2AADRA2BADRA2CASIC3 | |
| SCHEMBL20929568 | 0.79 | CD274 (0.51) | PNMTADRA2AADRA2BADRA2CASIC3 | |
| SCHEMBL30422918 | 0.79 | KDM4E (0.49) | PNMTADRA2AADRA2BADRA2CASIC3 | |
| Hydrochloric Acid SCHEMBL915241 | 0.78 | KDM4E (0.47) | PNMTADRA2AADRA2BADRA2CASIC3 | |
| SCHEMBL4788250 | 0.76 | PNMT (0.50) | PNMTADRA2AADRA2BADRA2CASIC3 | |
| SCHEMBL32660184 | 0.75 | PNMT (0.42) | PNMTADRA2AADRA2BADRA2CASIC3 | |
| SCHEMBL27651562 | 0.75 | PNMT (0.42) | PNMTADRA2AADRA2BADRA2CASIC3 | |
| SCHEMBL18389138 | 0.73 | PNMT (0.52) | PNMTADRA2AADRA2BADRA2CASIC3 | |
| SCHEMBL9782638 | 0.72 | CDC25B (0.37) | ADRA2AADRA2BADRA2C | |
| SCHEMBL232676 | 0.71 | ADCY6 (0.77) | PNMTADRA2AADRA2BADRA2CASIC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1430898-A1 | RECEPTOR ANTAGONIST | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2004-06-23 | — | — | EP | claimed |
| US-20040110826-A1 | Receptor Antagonists | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2004-06-10 | — | — | US | claimed |
| EP-1430898-A1 | RECEPTOR ANTAGONIST | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2004-06-23 | — | — | EP | disclosed |
| US-20040110826-A1 | Receptor Antagonists | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2004-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040110826-A1 | Receptor Antagonists | ADRA2C, OPRL1, ADRB1 | PNMT 323/4885ADRA2A 7/4885ADRA2B 13/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.