SCHEMBL6635706

SCHEMBL6635706

CCOC(=O)COc1ncccc1N

nearest known ligand 0.46

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.46
ALDH1A1 P00352 4/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
LMNA P02545 1/20 0.44
HSD17B10 Q99714 5/20 0.44
SQOR Q9Y6N5 1/20 0.43
GAA P10253 2/20 0.43
NPSR1 Q6W5P4 1/20 0.43
TBXAS1 P24557 1/20 0.43
TP53 P04637 2/20 0.43
HPGD P15428 2/20 0.43
HTT P42858 1/20 0.43
CHEK1 O14757 1/20 0.42
MAPT P10636 1/20 0.42
USP2 O75604 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.41
CASP1 P29466 1/20 0.41
TSHR P16473 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23424898 0.84 ALDH1A1 (0.48) KDM4EALDH1A1SMN1; SMN2LMNAHSD17B10
SCHEMBL3251631 0.84 GRM4 (0.40) ALDH1A1SMN1; SMN2LMNAHSD17B10
SCHEMBL5593086 0.83 KDM4E (0.47) KDM4EALDH1A1SMN1; SMN2LMNAHSD17B10
SCHEMBL17434668 0.83 ALDH1A1 (0.50) KDM4EALDH1A1SMN1; SMN2LMNAHSD17B10
SCHEMBL7369617 0.82 TBXAS1 (0.47) KDM4EALDH1A1LMNAHSD17B10TBXAS1
SCHEMBL18311966 0.82 ALDH1A1 (0.52) KDM4EALDH1A1SMN1; SMN2LMNAHSD17B10
SCHEMBL7422950 0.81 ALDH1A1 (0.48) KDM4EALDH1A1SMN1; SMN2LMNASQOR
SCHEMBL9850857 0.79 ALOX15 (0.46) KDM4EALDH1A1SMN1; SMN2GAATBXAS1
SCHEMBL6641775 0.78 USP2 (0.45) KDM4EALDH1A1SMN1; SMN2LMNAHSD17B10
SCHEMBL2825181 0.78 KDM4E (0.53) KDM4EALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1122244-B1 Uracil compounds and their use SUMITOMO CHEMICAL CO (JP) 2004-09-29 EP disclosed
US-6537948-B1 Have a wide range of herbicidal spectrum, and causes no phytotoxicity on crops SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-03-25 US disclosed
EP-1122244-A1 Uracil compounds and their use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-08-08 EP disclosed