Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 8/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.33 |
| ▸ | TSHR | P16473 | 5/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6636303 | 0.93 | KDM4E (0.34) | LMNASMN1; SMN2KDM4EALDH1A1MEN1 | |
| SCHEMBL3853401 | 0.80 | KDM4E (0.35) | LMNASMN1; SMN2KDM4EALDH1A1MEN1 | |
| SCHEMBL3849517 | 0.78 | KDM4E (0.34) | LMNASMN1; SMN2KDM4EALDH1A1MEN1 | |
| SCHEMBL3851899 | 0.71 | P2RX7 (0.38) | LMNASMN1; SMN2KDM4EALDH1A1MEN1 | |
| SCHEMBL4413794 | 0.71 | ALDH1A1 (0.36) | LMNASMN1; SMN2KDM4EALDH1A1MEN1 | |
| SCHEMBL6632031 | 0.71 | BCHE (0.37) | LMNASMN1; SMN2KDM4EALDH1A1MEN1 | |
| SCHEMBL3851010 | 0.69 | ADRB2 (0.37) | LMNASMN1; SMN2KDM4EALDH1A1MEN1 | |
| SCHEMBL6636006 | 0.69 | OXTR (0.32) | ALDH1A1KMT2APKM | |
| SCHEMBL6461059 | 0.69 | ADRB2 (0.35) | LMNAKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL6632870 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1000051-B1 | CARBAMYLOXY COMPOUNDS WHICH INHIBIT LEUKOCYTE ADHESION MEDIATED BY VLA-4 | ELAN PHARM INC (US) | 2004-05-19 | — | — | EP | claimed |