Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 4/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.46 |
| ▸ | FER | P16591 | 1/20 | 0.46 |
| ▸ | LTK | P29376 | 1/20 | 0.46 |
| ▸ | CDK8 | P49336 | 1/20 | 0.46 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.46 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.45 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.45 |
| ▸ | CDK2 | P24941 | 1/20 | 0.45 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.45 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.39 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6636727 | 1.00 | LRRK2 (0.46) | LRRK2MAOAMAOBPDGFRAFER | |
| SCHEMBL10814662 | 0.94 | LRRK2 (0.43) | LRRK2MAOAMAOBPDGFRAFER | |
| Isoindigo SCHEMBL12386233 | 0.76 | LRRK2 (0.67) | LRRK2MAOAMAOBPDGFRAFER | |
| Isoindigo SCHEMBL9899736 | 0.76 | LRRK2 (0.67) | LRRK2MAOAMAOBPDGFRAFER | |
| Isoindigo SCHEMBL9899740 | 0.76 | LRRK2 (0.67) | LRRK2MAOAMAOBPDGFRAFER | |
| Isoindigo SCHEMBL29349649 | 0.76 | LRRK2 (0.67) | LRRK2MAOAMAOBPDGFRAFER | |
| SCHEMBL16566263 | 0.76 | LRRK2 (0.52) | LRRK2MAOAMAOBPDGFRAFER | |
| SCHEMBL1593682 | 0.76 | LRRK2 (0.52) | LRRK2MAOAMAOBPDGFRAFER | |
| SCHEMBL3005009 | 0.73 | LRRK2 (0.48) | LRRK2MAOAMAOBPDGFRAFER | |
| SCHEMBL30546617 | 0.72 | AHR (0.50) | LRRK2MAOAMAOBPDGFRAFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040136932-A1 | Photoprotective cosmetic compositions comprising dibenzoylmethane compounds and 3-(2-azacycloalkylidene)-1,3-dihydroindol-2-one compounds | SOCIETE L'OREAL S.A. (FR) | 2004-07-15 | — | — | US | claimed |
| US-20040136931-A1 | Photoprotective cosmetic compositions comprising 3-(2-azacycloalkylidene)-1,3-dihydroindol-2-one compounds | SOCIETE L'OREAL S.A. (FR) | 2004-07-15 | — | — | US | claimed |
| EP-1424063-A1 | Cosmetic sunscreen compositions comprising 3-(2-azacycloalkylidene)-1,3-dihydro-indol-2-one derivatives and uses thereof | L'OREAL (FR) | 2004-06-02 | — | — | EP | claimed |
| EP-1424062-A1 | Screening composition containing at least one dibenzoylmethane derivative and at least one 3-(2-azacycloalkylidene)-1,3-dihydro-indol-2-one; photostabilisation process | L'OREAL (FR) | 2004-06-02 | — | — | EP | claimed |
| US-20040136932-A1 | Photoprotective cosmetic compositions comprising dibenzoylmethane compounds and 3-(2-azacycloalkylidene)-1,3-dihydroindol-2-one compounds | SOCIETE L'OREAL S.A. (FR) | 2004-07-15 | — | — | US | disclosed |
| US-20040136931-A1 | Photoprotective cosmetic compositions comprising 3-(2-azacycloalkylidene)-1,3-dihydroindol-2-one compounds | SOCIETE L'OREAL S.A. (FR) | 2004-07-15 | — | — | US | disclosed |
| EP-1424063-A1 | Cosmetic sunscreen compositions comprising 3-(2-azacycloalkylidene)-1,3-dihydro-indol-2-one derivatives and uses thereof | L'OREAL (FR) | 2004-06-02 | — | — | EP | disclosed |
| EP-1424062-A1 | Screening composition containing at least one dibenzoylmethane derivative and at least one 3-(2-azacycloalkylidene)-1,3-dihydro-indol-2-one; photostabilisation process | L'OREAL (FR) | 2004-06-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040136932-A1 | Photoprotective cosmetic compositions comprising dibenzoylmethane compounds and 3-(2-azacycloalkylidene)-1,3-dihydroindol-2-one compounds | DDT, DACH1, DLD | LRRK2 3796/4885MAOA 1017/4885MAOB 1491/4885 |
| US-20040136931-A1 | Photoprotective cosmetic compositions comprising 3-(2-azacycloalkylidene)-1,3-dihydroindol-2-one compounds | DDT, DHODH, UNG | LRRK2 4160/4885MAOA 318/4885MAOB 592/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.