Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 4/20 | 0.67 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.67 |
| ▸ | MAOA | P21397 | 1/20 | 0.67 |
| ▸ | MAOB | P27338 | 1/20 | 0.67 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.67 |
| ▸ | FER | P16591 | 1/20 | 0.67 |
| ▸ | LTK | P29376 | 1/20 | 0.67 |
| ▸ | CDK8 | P49336 | 1/20 | 0.67 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.67 |
| ▸ | GSK3B | P49841 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | IDO1 | P14902 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isoindigo SCHEMBL9899736 | 1.00 | LRRK2 (0.67) | LRRK2ACVR1MAOAMAOBPDGFRA | |
| Isoindigo SCHEMBL29349649 | 1.00 | LRRK2 (0.67) | LRRK2ACVR1MAOAMAOBPDGFRA | |
| Isoindigo SCHEMBL9899740 | 1.00 | LRRK2 (0.67) | LRRK2ACVR1MAOAMAOBPDGFRA | |
| SCHEMBL2589272 | 0.91 | LRRK2 (0.57) | LRRK2ACVR1MAOAMAOBPDGFRA | |
| SCHEMBL2589274 | 0.91 | LRRK2 (0.57) | LRRK2ACVR1MAOAMAOBPDGFRA | |
| SCHEMBL366728 | 0.84 | — | — | |
| SCHEMBL2420711 | 0.84 | LRRK2 (0.90) | LRRK2ACVR1MAOAMAOBPDGFRA | |
| Indirubin SCHEMBL9899338 | 0.83 | MAOA (0.64) | LRRK2ACVR1MAOAMAOBPDGFRA | |
| Indirubin SCHEMBL27678 | 0.83 | MAOA (0.64) | LRRK2ACVR1MAOAMAOBPDGFRA | |
| Indirubin SCHEMBL20535353 | 0.83 | MAOA (0.64) | LRRK2ACVR1MAOAMAOBPDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023155554-A1 | ELECTRICALLY CONDUCTIVE POLYMER, PREPARATION METHOD THEREFOR AND LIGHT-EMITTING DIODE | TCL科技集团股份有限公司 | 2023-08-24 | — | — | WO | disclosed |
| US-20170084839-A1 | ORGANIC SEMICONDUCTING COMPOUNDS | MERCK PATENT GMBH (DE) | 2017-03-23 | — | — | US | disclosed |
| US-20170073499-A1 | LATEX COMPRISING COLORANT AND METHODS OF MAKING THE SAME | U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS COLLATERAL AGENT | 2017-03-16 | — | — | US | disclosed |
| US-9580578-B2 | Latex comprising colorant and methods of making the same | XEROX CORPORATION (US) | 2017-02-28 | — | — | US | disclosed |
| US-20160243077-A1 | COMPOSITIONS AND METHODS TO IMPROVE THE THERAPEUTIC BENEFIT OF INDIRUBIN AND ANALOGS THEREOF, INCLUDING MEISOINDIGO | BROWN DENNIS M (US) | 2016-08-25 | — | — | US | disclosed |
| US-20160185771-A1 | Conjugate of Benzofuranone and Indole or Azaindole, and Preparation and Uses Thereof | LUODA BIOSCIENCES, INC. (CN) | 2016-06-30 | — | — | US | disclosed |
| US-20160024276-A1 | LATEX COMPRISING COLORANT AND METHODS OF MAKING THE SAME | U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS COLLATERAL AGENT | 2016-01-28 | — | — | US | disclosed |
| US-9213248-B2 | Latex comprising colorant and methods of making the same | XEROX CORPORATION (US) | 2015-12-15 | — | — | US | disclosed |
| WO-2015139802-A1 | ORGANIC SEMICONDUCTING COMPOUNDS | MERCK PATENT GMBH (DE) | 2015-09-24 | — | — | WO | disclosed |
| US-20150087687-A1 | COMPOSITIONS AND METHODS TO IMPROVE THE THERAPEUTIC BENEFIT OF INDIRUBIN AND ANALOGS THEREOF, INCLUDING MEISOINDIGO | BROWN DENNIS (US) | 2015-03-26 | — | — | US | disclosed |
| WO-2011027077-A2 | COMPOSITION COMPRISING A HYDROPHOBIC DYE, A SPECIFIC MINERAL AND/OR ORGANIC ALKALINE AGENT, A SPECIFIC COMPOUND (I) AND A SPECIFIC ORGANIC COMPOUND (II), AND USE THEREOF IN DYEING | L'OREAL (FR) | 2011-03-10 | — | — | WO | disclosed |
| WO-2011027076-A2 | DYEING METHOD CONSISTING IN APPLYING A METALLIC SALT AND A COMPOSITION CONTAINING A HYDROPHOBIC DYE AND A SPECIFIC COMPOUND | L'OREAL (FR) | 2011-03-10 | — | — | WO | disclosed |
| EP-2256166-A1 | Resin composition and process for producing resin molding | Sony Corporation (JP) | 2010-12-01 | — | — | EP | disclosed |
| US-20100144936-A1 | RESIN COMPOSITION AND PROCESS FOR PRODUCING RESIN MOLDING | SONY CORPORATION (JP) | 2010-06-10 | — | — | US | disclosed |
| US-20100144936-A1 | RESIN COMPOSITION AND PROCESS FOR PRODUCING RESIN MOLDING | SONY CORPORATION (JP) | 2010-06-10 | — | — | US | disclosed |
| US-20100137356-A1 | AZAINDOLE-INDOLE COUPLED DERIVATIVES, PREPARATION METHODS AND USES THEREOF | Cheng, Jingcai (CN) | 2010-06-03 | — | — | US | disclosed |
| US-20100137356-A1 | AZAINDOLE-INDOLE COUPLED DERIVATIVES, PREPARATION METHODS AND USES THEREOF | Cheng, Jingcai (CN) | 2010-06-03 | — | — | US | disclosed |
| US-7691928-B2 | Resin composition and process for producing resin molding | SONY CORPORATION (JP) | 2010-04-06 | — | — | US | disclosed |
| US-7691928-B2 | Resin composition and process for producing resin molding | SONY CORPORATION (JP) | 2010-04-06 | — | — | US | disclosed |
| EP-1218004-B1 | 5-METHYL INDIRUBIN FOR USE IN THE TREATMENT OF HUMAN SOLID TUMORS | FIEBIG HEINZ HERBERT (DE) | 2009-04-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170084839-A1 | ORGANIC SEMICONDUCTING COMPOUNDS | PPOX, OSTC, OCIAD1 | LRRK2 606/4885ACVR1 1360/4885MAOA 1388/4885 |
| US-20100137356-A1 | AZAINDOLE-INDOLE COUPLED DERIVATIVES, PREPARATION METHODS AND USES THEREOF | IDO1, IDO2, INMT | LRRK2 1918/4885ACVR1 1658/4885MAOA 78/4885 |
| US-20150087687-A1 | COMPOSITIONS AND METHODS TO IMPROVE THE THERAPEUTIC BENEFIT OF INDIRUBIN AND ANALOGS THEREOF, INCLUDING MEISOINDIGO | CYP7A1, CYP3A7, UGT2B7 | LRRK2 3651/4885ACVR1 2071/4885MAOA 217/4885 |
| US-20160243077-A1 | COMPOSITIONS AND METHODS TO IMPROVE THE THERAPEUTIC BENEFIT OF INDIRUBIN AND ANALOGS THEREOF, INCLUDING MEISOINDIGO | NEK9, NEK7, NEK3 | LRRK2 1497/4885ACVR1 3246/4885MAOA 698/4885 |
| US-20160185771-A1 | Conjugate of Benzofuranone and Indole or Azaindole, and Preparation and Uses Thereof | INMT, KMO, IDO1 | LRRK2 1571/4885ACVR1 1935/4885MAOA 288/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.