Isoindigo

Isoindigo

SCHEMBL9899740

O=C1Nc2ccccc2C1=C1C(=O)Nc2ccccc21

nearest known ligand 0.67

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LRRK2 Q5S007 4/20 0.67
ACVR1 Q04771 2/20 0.67
MAOA P21397 1/20 0.67
MAOB P27338 1/20 0.67
PDGFRA P16234 1/20 0.67
FER P16591 1/20 0.67
LTK P29376 1/20 0.67
CDK8 P49336 1/20 0.67
DYRK1B Q9Y463 1/20 0.67
GSK3B P49841 1/20 0.52
ALDH1A1 P00352 3/20 0.52
MAPT P10636 3/20 0.52
SMN1; SMN2 Q16637 3/20 0.52
NPSR1 Q6W5P4 2/20 0.52
IDO1 P14902 2/20 0.52
KDM4E B2RXH2 1/20 0.52
PKM P14618 1/20 0.52
MAPK1 P28482 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.50
NTRK1 P04629 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Isoindigo SCHEMBL9899736 1.00 LRRK2 (0.67) LRRK2ACVR1MAOAMAOBPDGFRA
Isoindigo SCHEMBL29349649 1.00 LRRK2 (0.67) LRRK2ACVR1MAOAMAOBPDGFRA
Isoindigo SCHEMBL12386233 1.00 LRRK2 (0.67) LRRK2ACVR1MAOAMAOBPDGFRA
SCHEMBL2589272 0.91 LRRK2 (0.57) LRRK2ACVR1MAOAMAOBPDGFRA
SCHEMBL2589274 0.91 LRRK2 (0.57) LRRK2ACVR1MAOAMAOBPDGFRA
SCHEMBL366728 0.84
SCHEMBL2420711 0.84 LRRK2 (0.90) LRRK2ACVR1MAOAMAOBPDGFRA
Indirubin SCHEMBL9899338 0.83 MAOA (0.64) LRRK2ACVR1MAOAMAOBPDGFRA
Indirubin SCHEMBL27678 0.83 MAOA (0.64) LRRK2ACVR1MAOAMAOBPDGFRA
Indirubin SCHEMBL20535353 0.83 MAOA (0.64) LRRK2ACVR1MAOAMAOBPDGFRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025050122-A1 MOLECULAR DESIGN OF ELECTROACTIVE SPECIES AND MATERIALS PROCESSING METHODS IN ORGANIC REDOX FLOW BATTERIES BIOZEN BATTERIES, INC. (US) 2025-03-06 WO claimed
US-10003025-B2 EDOT functionalized conjugated polymer and photodetector containing the same SOUTH UNIVERSITY OF SCIENCE AND TECHNOLOGY OF CHINA (CN) 2018-06-19 US claimed
US-20170279051-A1 EDOT Functionalized Conjugated Polymer And Photodetector Containing The Same SOUTH UNIVERSITY OF SCIENCE AND TECHNOLOGY OF CHNA (CN) 2017-09-28 US claimed
WO-2025050122-A1 MOLECULAR DESIGN OF ELECTROACTIVE SPECIES AND MATERIALS PROCESSING METHODS IN ORGANIC REDOX FLOW BATTERIES BIOZEN BATTERIES, INC. (US) 2025-03-06 WO disclosed
US-20230235388-A1 COMPOSITIONS AND METHODS FOR SEQUENCING USING AT LEAST ALTERING ELECTRICAL CHARACTERISTICS OF BRIDGES BETWEEN ELECTRODES ILLUMINA SINGAPORE PTE. LTD. (SG) 2023-07-27 US disclosed
EP-4172359-A1 COMPOSITIONS AND METHODS FOR SEQUENCING USING AT LEAST ALTERING ELECTRICAL CHARACTERISTICS OF BRIDGES BETWEEN ELECTRODES Illumina Singapore Pte. Ltd. (SG) 2023-05-03 EP disclosed
CN-114805325-A Multi-indolone Zig-Zag type bipolar small molecule and preparation method and application thereof 湖南工程学院 2022-07-29 CN disclosed
WO-2022005395-A1 COMPOSITIONS AND METHODS FOR SEQUENCING USING AT LEAST ALTERING ELECTRICAL CHARACTERISTICS OF BRIDGES BETWEEN ELECTRODES ILLUMINA SINGAPORE PTE. LTD. (SG) 2022-01-06 WO disclosed
US-10003025-B2 EDOT functionalized conjugated polymer and photodetector containing the same SOUTH UNIVERSITY OF SCIENCE AND TECHNOLOGY OF CHINA (CN) 2018-06-19 US disclosed
US-20170279051-A1 EDOT Functionalized Conjugated Polymer And Photodetector Containing The Same SOUTH UNIVERSITY OF SCIENCE AND TECHNOLOGY OF CHNA (CN) 2017-09-28 US disclosed
WO-2012078519-A2 3-ACYLIDENE-2-OXOINDOLE DERIVATIVES FOR INHIBITION OF TRANSGLUTAMINASE 2 NUMERATE, INC. (US) 2012-06-14 WO disclosed