Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 0.46 |
| ▸ | GPR88 | Q9GZN0 | 7/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6634314 | 0.80 | GPR88 (0.54) | GPR88ALDH1A1 | |
| SCHEMBL14019014 | 0.80 | GPR88 (0.54) | GPR88ALDH1A1 | |
| SCHEMBL16333280 | 0.79 | KMT2A (0.48) | GPR88ALDH1A1SMN1; SMN2 | |
| SCHEMBL16333281 | 0.79 | KMT2A (0.48) | GPR88ALDH1A1SMN1; SMN2 | |
| SCHEMBL16379888 | 0.77 | ALDH1A1 (0.42) | NR1I2ALDH1A1SLC2A1ACHESLC6A4 | |
| SCHEMBL17483396 | 0.76 | MEN1 (0.43) | GPR88ALDH1A1GAA | |
| SCHEMBL347372 | 0.76 | ALDH1A1 (0.54) | NR1I2ALDH1A1RECQLCYP3A4SMN1; SMN2 | |
| SCHEMBL5551011 | 0.76 | RAB9A (0.54) | NR1I2ALDH1A1RECQLCYP3A4SMN1; SMN2 | |
| SCHEMBL9818175 | 0.75 | ALDH1A1 (0.58) | NR1I2ALDH1A1RECQLCYP3A4SMN1; SMN2 | |
| SCHEMBL28784948 | 0.75 | NR1I2 (0.49) | NR1I2ALDH1A1RECQLCYP3A4SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1472260-A2 | THIENO(3,2-B)PYRIDONES AS ANTIVIRAL COMPOUNDS | PHARMACIA & UPJOHN COMPANY (US) | 2004-11-03 | — | — | EP | disclosed |
| WO-2003059878-A2 | THIENO (3, 2-B) PYRIDONES AS ANTIVIRAL COMPOUNDS | PHARMACIA & UPJOHN COMPANY (US) | 2003-07-24 | — | — | WO | disclosed |