Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.54 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.47 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6634314 | 1.00 | GPR88 (0.54) | GPR88AOC3ABCB11TSHRCYP2C9 | |
| SCHEMBL7067219 | 0.85 | GPR88 (0.51) | GPR88AOC3ABCB11TSHRCYP2C9 | |
| SCHEMBL8286096 | 0.82 | FAAH (0.49) | GPR88AOC3TSHRCA12CA1 | |
| SCHEMBL6637526 | 0.80 | NR1I2 (0.46) | GPR88ALDH1A1 | |
| SCHEMBL26809238 | 0.80 | MEN1 (0.47) | GPR88AOC3CA1CA2ALDH1A1 | |
| SCHEMBL17483396 | 0.80 | MEN1 (0.43) | GPR88TSHRALDH1A1PKMMAPT | |
| SCHEMBL6609429 | 0.80 | AOC3 (0.54) | AOC3TSHRALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL14533624 | 0.79 | TAS1R3 (0.45) | GPR88AOC3TSHRCA12CA1 | |
| SCHEMBL23100736 | 0.79 | GPR88 (0.68) | GPR88MEN1KMT2AFAAH | |
| SCHEMBL6256724 | 0.79 | GPR88 (0.68) | GPR88MEN1KMT2AFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080262005-A1 | Uracil-Type Gonadotropin-Releasing Hormone Receptor Antagonists and Methods Related Thereto | NEUROCRINE BIOSCIENCES, INC. (US) | 2008-10-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080262005-A1 | Uracil-Type Gonadotropin-Releasing Hormone Receptor Antagonists and Methods Related Thereto | GNRHR, FSHR, GHRHR | GPR88 156/4885AOC3 997/4885ABCB11 1654/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.