Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KMO | O15229 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | RXRA | P19793 | 2/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CTSA | P10619 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6672101 | 0.90 | PPOX (0.36) | MEN1MAPTKMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL6640252 | 0.82 | MEN1 (0.38) | MEN1MAPTKMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL6665164 | 0.82 | LMNA (0.41) | MAPTKMT2AL3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL6596714 | 0.79 | ALDH1A1 (0.39) | MEN1MAPTKMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL6666269 | 0.79 | MAPT (0.38) | MEN1MAPTKMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL6638642 | 0.78 | MEN1 (0.37) | MEN1MAPTKMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL6665284 | 0.78 | ALDH1A1 (0.38) | MEN1MAPTKMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL6639776 | 0.73 | PPOX (0.40) | MEN1KMT2AL3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL6643662 | 0.72 | MEN1 (0.46) | MEN1MAPTKMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL6639151 | 0.71 | BCAT1 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1122244-B1 | Uracil compounds and their use | SUMITOMO CHEMICAL CO (JP) | 2004-09-29 | — | — | EP | claimed |