Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | UGCG | Q16739 | 5/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.34 |
| ▸ | PPOX | P50336 | 1/20 | 0.34 |
| ▸ | BCAT2 | O15382 | 2/20 | 0.33 |
| ▸ | BCAT1 | P54687 | 2/20 | 0.33 |
| ▸ | DHODH | Q02127 | 3/20 | 0.33 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.33 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.33 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.33 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3825548 | 0.94 | MAPK8 (0.35) | MAPK8LMNAUGCGCYP3A4PPOX | |
| SCHEMBL6637334 | 0.92 | PPOX (0.34) | MAPK8LMNAUGCGCYP3A4PPOX | |
| SCHEMBL3850293 | 0.90 | BCAT1 (0.39) | LMNAPPOXBCAT2BCAT1DHODH | |
| SCHEMBL4572166 | 0.88 | UGCG (0.36) | MAPK8UGCGCYP3A4BCAT2BCAT1 | |
| SCHEMBL6641349 | 0.87 | LMNA (0.35) | LMNAPPOXDHODH | |
| SCHEMBL6641668 | 0.87 | BCAT1 (0.34) | MAPK8UGCGCYP3A4BCAT2BCAT1 | |
| SCHEMBL121222 | 0.87 | PPOX (0.41) | MAPK8UGCGCYP3A4PPOXBCAT2 | |
| SCHEMBL29351496 | 0.87 | PPOX (0.41) | MAPK8UGCGCYP3A4PPOXBCAT2 | |
| SCHEMBL2594502 | 0.86 | BCAT1 (0.41) | MAPK8UGCGCYP3A4PPOXBCAT2 | |
| SCHEMBL6644010 | 0.86 | GPBAR1 (0.35) | LMNAPPOXBCAT2BCAT1DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1122244-B1 | Uracil compounds and their use | SUMITOMO CHEMICAL CO (JP) | 2004-09-29 | — | — | EP | disclosed |
| US-6537948-B1 | Have a wide range of herbicidal spectrum, and causes no phytotoxicity on crops | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2003-03-25 | — | — | US | disclosed |
| EP-1122244-A1 | Uracil compounds and their use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-08-08 | — | — | EP | disclosed |