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SCHEMBL3825548

SCHEMBL3825548

COC(=O)COc1ncccc1Oc1cc(-n2c(=O)cc(C(F)(F)F)n(C)c2=O)c(F)cc1Cl

nearest known ligand 0.35

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ MAPK8 P45983 1/20 0.35
▸ BCAT1 P54687 3/20 0.34
▸ BCAT2 O15382 2/20 0.34
▸ UGCG Q16739 5/20 0.34
▸ CYP3A4 P08684 4/20 0.34
▸ HTR1A P08908 1/20 0.33
▸ DRD2 P14416 1/20 0.33
▸ ADRA1A P35348 1/20 0.33
▸ DHODH Q02127 3/20 0.33
▸ P2RY1 P47900 1/20 0.33
▸ LMNA P02545 1/20 0.32
▸ PPOX P50336 1/20 0.32
▸ ROCK2 O75116 1/20 0.32
▸ HTR2A P28223 1/20 0.32
▸ HTR2C P28335 1/20 0.32
▸ HTR2B P41595 1/20 0.32
▸ SCN9A Q15858 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6637334 0.97 PPOX (0.34) MAPK8BCAT1BCAT2UGCGCYP3A4
SCHEMBL6639709 0.94 MAPK8 (0.35) MAPK8BCAT1BCAT2UGCGCYP3A4
SCHEMBL4572166 0.92 UGCG (0.36) MAPK8BCAT1BCAT2UGCGCYP3A4
SCHEMBL29351496 0.92 PPOX (0.41) MAPK8BCAT1BCAT2UGCGCYP3A4
SCHEMBL121222 0.92 PPOX (0.41) MAPK8BCAT1BCAT2UGCGCYP3A4
SCHEMBL29709277 0.92 BCAT1 (0.34) MAPK8BCAT1BCAT2UGCGCYP3A4
Benzene SCHEMBL21843346 0.92 BCAT1 (0.34) MAPK8BCAT1BCAT2UGCGCYP3A4
SCHEMBL1959750 0.92 BCAT1 (0.34) MAPK8BCAT1BCAT2UGCGCYP3A4
SCHEMBL30724506 0.92 PPOX (0.33) MAPK8BCAT1BCAT2UGCGCYP3A4
SCHEMBL27136206 0.92 PPOX (0.33) MAPK8BCAT1BCAT2UGCGCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1122244-B1 Uracil compounds and their use SUMITOMO CHEMICAL CO (JP) 2004-09-29 — — EP claimed
US-6537948-B1 Have a wide range of herbicidal spectrum, and causes no phytotoxicity on crops SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-03-25 — — US claimed
EP-1122244-A1 Uracil compounds and their use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-08-08 — — EP claimed
US-11827896-B2 Plants having increased tolerance to herbicides BASF Agro B.V. (NL) 2023-11-28 — — US disclosed
US-11766044-B2 Method for controlling PPO resistant weeds BASF SE (DE) 2023-09-26 — — US disclosed
US-20230279420-A1 PLANTS HAVING INCREASED TOLERANCE TO HERBICIDES BASF AGRO BV (NL) 2023-09-07 — — US disclosed
US-20230036177-A1 Plants Having Increased Tolerance to Herbicides BASF AGRO BV (NL) 2023-02-02 — — US disclosed
US-11234438-B2 Protoporphyrinogen oxidase inhibitor mixtures VALENT U.S.A., LLC (US) 2022-02-01 — — US disclosed
US-11234438-B2 Protoporphyrinogen oxidase inhibitor mixtures VALENT U.S.A., LLC (US) 2022-02-01 — — US disclosed
EP-2861742-B1 PLANTS HAVING INCREASED TOLERANCE TO HERBICIDES BASF AGRO BV (NL) 2021-12-29 — — EP disclosed
US-20210380999-A1 PLANTS HAVING INCREASED TOLERANCE TO HERBICIDES BASF AGRO BV (NL) 2021-12-09 — — US disclosed
US-7157579-B2 Process for producing pyridine compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-01-02 — — US disclosed
US-20060189484-A1 PYRIDONE COMPOUNDS USEFUL FOR PRODUCING PYRIDINE COMPOUNDS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2006-08-24 — — US disclosed
US-20050154210-A1 Process for production of phenoxy-substituted 2-pyridone compounds SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2005-07-14 — — US disclosed
EP-1538145-A1 PROCESS FOR PRODUCTION OF PHENOXY-SUBSTITUTED 2-PYRIDONE COMPOUNDS Sumitomo Chemical Company, Limited (JP) 2005-06-08 — — EP disclosed
US-20040254077-A1 Process for producing pyridine compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-12-16 — — US disclosed
EP-1122244-B1 Uracil compounds and their use SUMITOMO CHEMICAL CO (JP) 2004-09-29 — — EP disclosed
EP-1422227-A1 PROCESS FOR PRODUCING PYRIDINE COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-05-26 — — EP disclosed
US-6537948-B1 Have a wide range of herbicidal spectrum, and causes no phytotoxicity on crops SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-03-25 — — US disclosed
EP-1122244-A1 Uracil compounds and their use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-08-08 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230036177-A1 Plants Having Increased Tolerance to Herbicides PPOX, PNPO, PAOX MAPK8 3530/4885BCAT1 638/4885BCAT2 867/4885
US-20040254077-A1 Process for producing pyridine compound CBR1, CBR3, CYP4B1 MAPK8 1337/4885BCAT1 1753/4885BCAT2 1515/4885
US-11827896-B2 Plants having increased tolerance to herbicides AGPS, PPOX, DAO MAPK8 3767/4885BCAT1 425/4885BCAT2 830/4885
US-20060189484-A1 PYRIDONE COMPOUNDS USEFUL FOR PRODUCING PYRIDINE COMPOUNDS CBR3, CBR1, PNPO MAPK8 2791/4885BCAT1 1359/4885BCAT2 1679/4885
US-20050154210-A1 Process for production of phenoxy-substituted 2-pyridone compounds PDK2, ME1, PDXK MAPK8 959/4885BCAT1 774/4885BCAT2 489/4885
US-11766044-B2 Method for controlling PPO resistant weeds PPOX, PNPO, NOTUM MAPK8 2743/4885BCAT1 1472/4885BCAT2 1540/4885
US-11234438-B2 Protoporphyrinogen oxidase inhibitor mixtures PPOX, ACOX1, CYP51A1 MAPK8 2135/4885BCAT1 774/4885BCAT2 709/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.