Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 8/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 8/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.34 |
| ▸ | TYMS | P04818 | 1/20 | 0.34 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6637708 | 0.74 | MTNR1A (0.49) | KDM4EALDH1A1HPGD | |
| SCHEMBL5368108 | 0.74 | KDM4E (0.57) | KDM4EALDH1A1LMNAMAPTHPGD | |
| Hydrochloric Acid SCHEMBL10617650 | 0.72 | HTR2A (0.46) | SLC6A2SLC6A4SLC6A3HTR2AHTR2C | |
| SCHEMBL29593942 | 0.71 | HTR2A (0.52) | SLC6A2SLC6A4SLC6A3HTR2AHTR2C | |
| SCHEMBL714536 | 0.71 | HTR2A (0.52) | SLC6A2SLC6A4SLC6A3HTR2AHTR2C | |
| SCHEMBL11131288 | 0.70 | ALDH1A1 (0.40) | KDM4EALDH1A1LMNAMAPTHPGD | |
| Hydrochloric Acid SCHEMBL10615532 | 0.70 | DRD3 (0.58) | CYP2D6CYP1A2TSHR | |
| SCHEMBL10770008 | 0.70 | SIGMAR1 (0.43) | — | |
| Hydrochloric Acid SCHEMBL1571970 | 0.69 | IDO1 (0.55) | SLC6A2SLC6A4SLC6A3HTR2AHTR2C | |
| SCHEMBL17448805 | 0.69 | TYMS (0.43) | KDM4EALDH1A1LMNAMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1047664-B1 | NOVEL TRICYCLIC COMPOUNDS, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SERVIER LAB (FR) | 2004-05-19 | — | — | EP | disclosed |
| US-6423870-B1 | ANTICOAGULANTS; CIRCADIAN RHYTHM DISORDERS; SLEEP DISORDERS | LES LABORATOIRES SERVIER (FR) | 2002-07-23 | — | — | US | disclosed |