Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGPAT2 | O15120 | 2/20 | 0.49 |
| ▸ | PRKACA | P17612 | 3/20 | 0.46 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.46 |
| ▸ | CDK1 | P06493 | 2/20 | 0.46 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.46 |
| ▸ | PRKACG | P22612 | 2/20 | 0.46 |
| ▸ | PRKACB | P22694 | 2/20 | 0.46 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.46 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.46 |
| ▸ | CSNK1E | P49674 | 2/20 | 0.46 |
| ▸ | CLK1 | P49759 | 2/20 | 0.46 |
| ▸ | GSK3B | P49841 | 2/20 | 0.46 |
| ▸ | CSNK1G2 | P78368 | 2/20 | 0.46 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.46 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.46 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.46 |
| ▸ | CSNK1G1 | Q9HCP0 | 2/20 | 0.46 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.46 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28509535 | 0.84 | LTA4H (0.53) | PRKACACSNK1A1CSNK1DCSNK1G2CSNK1G1 | |
| SCHEMBL30507524 | 0.84 | LTA4H (0.53) | PRKACACSNK1A1CSNK1DCSNK1G2CSNK1G1 | |
| SCHEMBL4282091 | 0.83 | AGPAT2 (0.53) | AGPAT2CCR5HSP90AA1PTGER1SLC6A4 | |
| SCHEMBL6638721 | 0.81 | FEN1 (0.48) | PRKACASMN1; SMN2AURKAHSP90AA1ADORA2A | |
| SCHEMBL28286296 | 0.80 | CCR5 (0.55) | CCR5HTTSMN1; SMN2ALDH1A1LRRK2 | |
| SCHEMBL30835001 | 0.80 | CCR5 (0.55) | CCR5HTTSMN1; SMN2ALDH1A1LRRK2 | |
| SCHEMBL17049367 | 0.79 | CCR5 (0.56) | CCR5HTTSMN1; SMN2ALDH1A1PTGER1 | |
| SCHEMBL4215294 | 0.79 | CDK5 (0.52) | AGPAT2PRKACACCNB2CDK1CCNB1 | |
| SCHEMBL26621373 | 0.78 | FEN1 (0.53) | PRKACAAURKAHSP90AA1ADORA2A | |
| SCHEMBL6669227 | 0.78 | ENPP2 (0.48) | PRKACACLK1GSK3BCDK5CDK5R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240150325-A1 | NOVEL COMPOUND AS PROTEIN KINASE INHIBITORS | LG CHEM, LTD. (KR) | 2024-05-09 | — | — | US | disclosed |
| EP-4273140-A1 | NOVEL COMPOUND AS PROTEIN KINASE INHIBITOR | Lg Chem, Ltd. (KR) | 2023-11-08 | — | — | EP | disclosed |
| WO-2022169248-A1 | NOVEL COMPOUND AS PROTEIN KINASE INHIBITOR | 주식회사 엘지화학 | 2022-08-11 | — | — | WO | disclosed |
| EP-1412327-A2 | INHIBITORS OF PROTEIN KINASE FOR THE TREATMENT OF DISEASE | LG Biomedical Institute (US) | 2004-04-28 | — | — | EP | disclosed |
| US-20030208067-A1 | Inhibitors of protein kinase for the treatment of disease | LG BIOMEDICAL INSTITUTE | 2003-11-06 | — | — | US | disclosed |
| US-20030187007-A1 | Inhibitors of protein kinase for the treatment of disease | LG BIOMEDICAL INSTITUTE | 2003-10-02 | — | — | US | disclosed |
| WO-2002096867-A2 | INHIBITORS OF PROTEIN KINASE FOR THE TREATMENT OF DISEASE | LG BIOMEDICAL INSTITUTE (US) | 2002-12-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240150325-A1 | NOVEL COMPOUND AS PROTEIN KINASE INHIBITORS | MAP3K20, SBK3, MAPKAPK2 | AGPAT2 3098/4885PRKACA 101/4885CCNB2 1762/4885 |
| US-20030208067-A1 | Inhibitors of protein kinase for the treatment of disease | MAP3K20, MAP3K1, MAP3K2 | AGPAT2 4075/4885PRKACA 62/4885CCNB2 1399/4885 |
| US-20030187007-A1 | Inhibitors of protein kinase for the treatment of disease | MAP3K20, MAP3K1, MAP3K2 | AGPAT2 4075/4885PRKACA 62/4885CCNB2 1399/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.