SCHEMBL6640939

SCHEMBL6640939

COC(=O)COc1nc(Cl)ccc1Oc1cc(-n2c(=O)cc(C(F)(F)F)n(C)c2=O)c(F)cc1[N+](=O)[O-]

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.32
FGFR4 P22455 1/20 0.31
MERTK Q12866 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6641538 0.91 TXNRD1 (0.34)
SCHEMBL6641209 0.90 LMNA (0.32)
SCHEMBL6638630 0.88 MEN1 (0.31) MAPT
SCHEMBL3241978 0.88 MEN1 (0.36) MAPT
SCHEMBL6640527 0.88
SCHEMBL6639155 0.86
SCHEMBL6245011 0.86 ALDH1A1 (0.36) MAPT
SCHEMBL6644384 0.83 TDP1 (0.31) MAPT
SCHEMBL6638620 0.82 CXCR1 (0.33) MAPT
SCHEMBL6638783 0.82 PLA2G7 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1122244-B1 Uracil compounds and their use SUMITOMO CHEMICAL CO (JP) 2004-09-29 EP disclosed
US-6537948-B1 Have a wide range of herbicidal spectrum, and causes no phytotoxicity on crops SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-03-25 US disclosed
EP-1122244-A1 Uracil compounds and their use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-08-08 EP disclosed