Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 5/20 | 0.39 |
| ▸ | DDB1 | Q16531 | 4/20 | 0.39 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | STK33 | Q9BYT3 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 4/20 | 0.35 |
| ▸ | PRSS12 | P56730 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4303217 | 0.83 | STK33 (0.43) | CRBNDDB1MAP1LC3BALDH1A1HPGD | |
| SCHEMBL4310755 | 0.78 | L3MBTL1 (0.42) | CRBNDDB1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL4316646 | 0.78 | ALDH1A1 (0.41) | CRBNDDB1MAP1LC3BALDH1A1HPGD | |
| SCHEMBL6216650 | 0.76 | ALDH1A1 (0.38) | CRBNDDB1MAP1LC3BALDH1A1HPGD | |
| SCHEMBL4307094 | 0.72 | F10 (0.45) | CRBNDDB1MAP1LC3BALDH1A1HPGD | |
| SCHEMBL4312090 | 0.72 | KMT2A (0.45) | CRBNDDB1MAP1LC3BALDH1A1HPGD | |
| SCHEMBL4305880 | 0.72 | ACHE (0.41) | CRBNDDB1MAP1LC3BALDH1A1HPGD | |
| SCHEMBL4305977 | 0.70 | ACHE (0.54) | ALDH1A1HPGDSMN1; SMN2STK33KDM4E | |
| SCHEMBL4311995 | 0.70 | ACHE (0.43) | ALDH1A1HPGDSMN1; SMN2STK33KDM4E | |
| SCHEMBL5780391 | 0.69 | ACHE (0.42) | ALDH1A1HPGDSMN1; SMN2STK33KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1414817-A1 | SUBSTITUTED ISOINDOLES AND E USE THEREOF | Bayer HealthCare AG (DE) | 2004-05-06 | — | — | EP | disclosed |
| WO-2003011858-A1 | SUBSTITUTED ISOINDOLES AND E USE THEREOF | BAYER HEALTHCARE AG (DE) | 2003-02-13 | — | — | WO | disclosed |