Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11120384 | 0.86 | MAOA (0.34) | POLBMAPTKDM4EALDH1A1MAOA | |
| SCHEMBL664362 | 0.86 | CYP19A1 (0.46) | POLBABCG2MAPTCRHBPCRHR2 | |
| SCHEMBL29085240 | 0.86 | CYP19A1 (0.47) | ALOX5POLBABCG2MAPTCRHBP | |
| SCHEMBL11119917 | 0.84 | LMNA (0.40) | POLBMAPTCYP19A1ALDH1A1KMT2A | |
| SCHEMBL10606553 | 0.84 | AR (0.35) | POLBABCG2MAPTCRHBPCRHR2 | |
| SCHEMBL1201689 | 0.83 | KDM4E (0.40) | ALOX5POLBMAPTKDM4ECYP19A1 | |
| SCHEMBL29204371 | 0.80 | CYP19A1 (0.42) | POLBABCG2MAPTKDM4ECYP19A1 | |
| SCHEMBL11121382 | 0.79 | CDK1 (0.47) | MAPTGAA | |
| SCHEMBL661409 | 0.79 | CYP19A1 (0.53) | POLBABCG2MAPTCYP19A1ABCB1 | |
| SCHEMBL1200431 | 0.78 | PTPN1 (0.45) | ALOX5POLBCYP19A1KMT2ACA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103585194-A | Application of Aleuritopteris argentea Fee extract in preparation of drugs treating AIDS | JINAN XINGYI MED TECH CO LTD | 2014-02-19 | — | — | CN | claimed |
| CN-103585192-A | Preparation method and application of Aleuritopteris argentea Fee extract | JINAN XINGYI MED TECH CO LTD | 2014-02-19 | — | — | CN | claimed |
| CN-103585193-A | Application of Aleuritopteris argentea Fee extract in preparation of drugs treating leukemia | JINAN XINGYI MED TECH CO LTD | 2014-02-19 | — | — | CN | claimed |
| CN-103585196-A | Application of silvery aleuritopteris herb extract in preparation of anticancer drugs | JINAN XINGYI MED TECH CO LTD | 2014-02-19 | — | — | CN | claimed |
| CN-103585196-B | Aleuritopteris argentea (Gmel.) Fee extract is preparing the application in cancer therapy drug | ZHOU JIEHUA (CN) | 2016-01-20 | — | — | CN | disclosed |
| CN-103585193-B | The application of Aleuritopteris argentea (Gmel.) Fee extract in preparation treatment leukemia medicament | BAI XIAOYING (CN) | 2016-01-20 | — | — | CN | disclosed |
| CN-103585192-B | A kind of preparation method of Aleuritopteris argentea (Gmel.) Fee extract and application thereof | YU LI (CN) | 2015-10-28 | — | — | CN | disclosed |
| CN-103585194-B | The application of Aleuritopteris argentea (Gmel.) Fee extract in preparation treatment AIDS-treating medicine | SUN CHENGYONG (CN) | 2015-10-28 | — | — | CN | disclosed |
| CN-103585194-A | Application of Aleuritopteris argentea Fee extract in preparation of drugs treating AIDS | JINAN XINGYI MED TECH CO LTD | 2014-02-19 | — | — | CN | disclosed |
| CN-103585193-A | Application of Aleuritopteris argentea Fee extract in preparation of drugs treating leukemia | JINAN XINGYI MED TECH CO LTD | 2014-02-19 | — | — | CN | disclosed |
| CN-103585192-A | Preparation method and application of Aleuritopteris argentea Fee extract | JINAN XINGYI MED TECH CO LTD | 2014-02-19 | — | — | CN | disclosed |
| CN-103585196-A | Application of silvery aleuritopteris herb extract in preparation of anticancer drugs | JINAN XINGYI MED TECH CO LTD | 2014-02-19 | — | — | CN | disclosed |
| US-20120046353-A1 | CLEISTOCALYX OPERCULATUS-DERIVED COMPOUNDS HAVING INHIBITORY ACTIVITIES AGAINST AVIAN AND SWINE INFLUENZA VIRUSES OR NOVEL INFLUENZA VIRUS | CHOONG ANG VACCINE LAB. (KR) | 2012-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120046353-A1 | CLEISTOCALYX OPERCULATUS-DERIVED COMPOUNDS HAVING INHIBITORY ACTIVITIES AGAINST AVIAN AND SWINE INFLUENZA VIRUSES OR NOVEL INFLUENZA VIRUS | PIGS, CLEC4M, ENGASE | ALOX5 2840/4885POLB 3306/4885ABCG2 1926/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.