Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | PGK1 | P00558 | 1/20 | 0.38 |
| ▸ | PGK2 | P07205 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | FBP1 | P09467 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11096330 | 0.81 | CYP3A4 (0.45) | CYP3A4ALDH1A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL3347914 | 0.80 | ALDH1A1 (0.46) | ALDH1A1TDP1LMNATSHRCA2 | |
| SCHEMBL1775211 | 0.80 | MMP8 (0.46) | CYP3A4ALDH1A1TDP1TSHRMAPT | |
| Hydrochloric Acid SCHEMBL10917756 | 0.78 | ALDH1A1 (0.44) | ALDH1A1TDP1LMNATSHRCA2 | |
| SCHEMBL664342 | 0.78 | ALDH1A1 (0.44) | ALDH1A1TDP1LMNATSHRCA2 | |
| SCHEMBL11037804 | 0.75 | TDP1 (0.48) | CYP3A4ALDH1A1TDP1LMNATSHR | |
| SCHEMBL8613678 | 0.75 | HPGD (0.43) | ALDH1A1TDP1LMNATSHRCA2 | |
| SCHEMBL7209760 | 0.72 | MAPT (0.42) | CYP3A4ALDH1A1TDP1LMNATSHR | |
| SCHEMBL12002753 | 0.71 | TDP1 (0.47) | CYP3A4ALDH1A1TDP1LMNATSHR | |
| SCHEMBL11039147 | 0.71 | CA2 (0.48) | ALDH1A1TDP1LMNATSHRCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009023718-A2 | NOVEL ACTIVATORS OF GLUCOKINASE | METABASIS THERAPEUTICS, INC. (US) | 2009-02-19 | — | — | WO | disclosed |