Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.33 |
| ▸ | TRPC6 | Q9Y210 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | DNM1L | O00429 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | SREBF2 | Q12772 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6646017 | 0.86 | SIRT1 (0.39) | SIRT1ADRB2ADRB1ADRB3MAPT | |
| SCHEMBL6645614 | 0.85 | SIRT1 (0.37) | SIRT1MAPTSMN1; SMN2TP53DNM1L | |
| SCHEMBL6497778 | 0.84 | SREBF2 (0.38) | SIRT1MAPTSMN1; SMN2LCKSREBF2 | |
| SCHEMBL6491615 | 0.82 | SREBF2 (0.39) | SIRT1MAPTLCKNPC1RAB9A | |
| SCHEMBL6490015 | 0.82 | GCGR (0.41) | MAPTSMN1; SMN2LCKGAASREBF2 | |
| SCHEMBL6491198 | 0.81 | APOB (0.39) | MAPTSMN1; SMN2TP53SREBF2POLB | |
| SCHEMBL6648076 | 0.81 | SREBF2 (0.36) | SIRT1MAPTTP53LCKGAA | |
| SCHEMBL6499352 | 0.80 | MAPT (0.39) | MAPTSMN1; SMN2LCKSREBF2KDM4E | |
| SCHEMBL6795163 | 0.79 | KMT2A (0.38) | SIRT1MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL6499741 | 0.79 | SREBF2 (0.40) | SIRT1MAPTSMN1; SMN2LCKSREBF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040133008-A1 | Amide compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-07-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040133008-A1 | Amide compounds | APOB, APOL1, LDLR | SIRT1 1393/4885ADRB2 23/4885ADRB1 16/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.