Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.39 |
| ▸ | CTPS1 | P17812 | 2/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.35 |
| ▸ | TRPC6 | Q9Y210 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | CTPS2 | Q9NRF8 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | DNM1L | O00429 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6645917 | 0.86 | SMN1; SMN2 (0.50) | ADRB2ADRB1ADRB3KMT2APOLB | |
| SCHEMBL6648108 | 0.86 | KIF18A (0.38) | ADRB2ADRB1ADRB3KMT2AGAA | |
| SCHEMBL6644657 | 0.86 | SIRT1 (0.37) | SIRT1ADRB2ADRB1ADRB3KMT2A | |
| SCHEMBL6649392 | 0.82 | MAPT (0.39) | ADRB2ADRB1ADRB3TRPC3TRPC6 | |
| SCHEMBL6646880 | 0.82 | RXFP1 (0.37) | SIRT1MAPTSMN1; SMN2TP53RXFP1 | |
| SCHEMBL6643270 | 0.80 | ALDH1A1 (0.45) | ADRB2ADRB1ADRB3KMT2APOLB | |
| SCHEMBL6648171 | 0.80 | CTPS1 (0.40) | CTPS1KMT2ATRPC3TRPC6POLB | |
| SCHEMBL6646979 | 0.80 | MAPT (0.40) | ADRB2ADRB1ADRB3KMT2APOLB | |
| SCHEMBL6490959 | 0.79 | TP53 (0.43) | POLBMAPTTP53RXFP1NPC1 | |
| SCHEMBL6645513 | 0.77 | SMN1; SMN2 (0.39) | ADRB2ADRB1ADRB3KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040133008-A1 | Amide compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-07-08 | — | — | US | disclosed |
| WO-2004039795-A2 | AMIDE COMPOUNDS FOR THE TREATMENT OF HYPERLIPIDEMIA | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-05-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040133008-A1 | Amide compounds | APOB, APOL1, LDLR | SIRT1 1393/4885CTPS1 2778/4885ADRB2 23/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.