Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMD14 | O00487 | 1/20 | 0.38 |
| ▸ | TDP2 | O95551 | 2/20 | 0.38 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.37 |
| ▸ | LPL | P06858 | 1/20 | 0.37 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.37 |
| ▸ | TOP1 | P11387 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.33 |
| ▸ | ERN1 | O75460 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6644437 | 0.72 | LPL (0.38) | TDP2SRD5A1LPLLIPGTOP1 | |
| SCHEMBL6586181 | 0.70 | — | — | |
| SCHEMBL16166770 | 0.65 | TAAR1 (0.48) | PSMD14TDP2LPLLIPGTOP1 | |
| SCHEMBL21534752 | 0.63 | TDP2 (0.46) | TDP2LPLLIPGPGRTAAR1 | |
| SCHEMBL21868406 | 0.63 | PRMT6 (0.36) | TDP2SRD5A1LPLLIPGTOP1 | |
| SCHEMBL9511306 | 0.62 | TAAR1 (0.46) | PSMD14TDP2LPLLIPGTOP1 | |
| SCHEMBL16482595 | 0.61 | LPL (0.40) | TDP2SRD5A1LPLLIPGPGR | |
| SCHEMBL19354601 | 0.61 | TAAR1 (0.44) | PSMD14TDP2LPLLIPGPGR | |
| SCHEMBL394300 | 0.61 | TAAR1 (0.76) | LPLLIPGPGRTAAR1ALDH1A1 | |
| SCHEMBL8349771 | 0.60 | PTGS1 (0.45) | TDP2SRD5A1LPLLIPGTOP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0883616-B1 | DIHYDROBENZOFURAN AND RELATED COMPOUNDS USEFUL AS ANTI-INFLAMMATORY AGENTS | UNIV VANDERBILT (US) | 2004-08-25 | — | — | EP | disclosed |