Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 3/20 | 0.46 |
| ▸ | HTR2B | P41595 | 3/20 | 0.46 |
| ▸ | HTR2A | P28223 | 2/20 | 0.46 |
| ▸ | EIF2AK3 | Q9NZJ5 | 1/20 | 0.45 |
| ▸ | NPY2R | P49146 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | SMO | Q99835 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6646117 | 0.99 | MAPT (0.48) | SMN1; SMN2MAPTGAAL3MBTL1HTR2C | |
| SCHEMBL6643967 | 0.91 | GAA (0.51) | SMN1; SMN2MAPTGAAL3MBTL1HTR2C | |
| SCHEMBL6645751 | 0.91 | ALDH1A1 (0.53) | SMN1; SMN2MAPTL3MBTL1HTR2CHTR2B | |
| SCHEMBL6645864 | 0.91 | GAA (0.46) | SMN1; SMN2MAPTGAAL3MBTL1HTR2C | |
| SCHEMBL6646057 | 0.91 | HTR2C (0.50) | SMN1; SMN2MAPTHTR2CHTR2BHTR2A | |
| SCHEMBL6646675 | 0.91 | GAA (0.46) | SMN1; SMN2MAPTGAAL3MBTL1HTR2C | |
| SCHEMBL6647734 | 0.91 | GAA (0.49) | SMN1; SMN2MAPTGAAL3MBTL1HTR2C | |
| SCHEMBL6643075 | 0.90 | EIF2AK3 (0.45) | SMN1; SMN2MAPTHTR2CHTR2BHTR2A | |
| SCHEMBL6648311 | 0.90 | SMN1; SMN2 (0.45) | SMN1; SMN2MAPTGAAL3MBTL1HTR2C | |
| SCHEMBL6648416 | 0.89 | HTR2C (0.44) | SMN1; SMN2MAPTL3MBTL1HTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040133008-A1 | Amide compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-07-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040133008-A1 | Amide compounds | APOB, APOL1, LDLR | SMN1; SMN2 1836/4885MAPT 4101/4885GAA 3155/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.