Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD1 | Q9Y239 | 5/20 | 0.38 |
| ▸ | TNF | P01375 | 3/20 | 0.38 |
| ▸ | NOD2 | Q9HC29 | 3/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6643995 | 0.88 | NOD1 (0.41) | NOD1TNFNOD2PLAUKDR | |
| SCHEMBL6648871 | 0.86 | SCN10A (0.37) | NOD1PLAUKDRMEN1KMT2A | |
| SCHEMBL6645494 | 0.82 | NOD1 (0.39) | NOD1TNFNOD2PLAUKDR | |
| SCHEMBL6648162 | 0.81 | PLAU (0.42) | NOD1TNFNOD2PLAUMEN1 | |
| SCHEMBL6490283 | 0.75 | NOD1 (0.39) | NOD1TNFNOD2KDRMEN1 | |
| SCHEMBL6649475 | 0.75 | TMPRSS2 (0.47) | MEN1KMT2ASMN1; SMN2KDM4ETMPRSS2 | |
| SCHEMBL6647429 | 0.69 | NOD1 (0.45) | NOD1TNFNOD2PLAUMEN1 | |
| SCHEMBL6644871 | 0.67 | F2 (0.50) | PLAUMEN1KMT2A | |
| SCHEMBL6644698 | 0.66 | EIF2AK3 (0.44) | SMN1; SMN2LMNARAB9ANPC1 | |
| SCHEMBL6644942 | 0.66 | PLAU (0.40) | NOD1PLAUMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040133008-A1 | Amide compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-07-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040133008-A1 | Amide compounds | APOB, APOL1, LDLR | NOD1 850/4885TNF 3852/4885NOD2 1085/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.