Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD1 | Q9Y239 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 8/20 | 0.39 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.35 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | TNF | P01375 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NOD2 | Q9HC29 | 2/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6643995 | 0.83 | NOD1 (0.41) | NOD1LMNASMN1; SMN2PLAUABCB1 | |
| SCHEMBL6645706 | 0.82 | NOD1 (0.38) | NOD1LMNASMN1; SMN2PLAUMEN1 | |
| SCHEMBL6647009 | 0.82 | PLAU (0.44) | NOD1LMNASMN1; SMN2PLAUABCB1 | |
| SCHEMBL6648871 | 0.80 | SCN10A (0.37) | NOD1LMNASMN1; SMN2PLAUMEN1 | |
| SCHEMBL6490283 | 0.75 | NOD1 (0.39) | NOD1LMNASMN1; SMN2ABCB1MEN1 | |
| SCHEMBL6648762 | 0.74 | SIGMAR1 (0.52) | PLAUABCB1ABCG2POLBUSP2 | |
| SCHEMBL6649201 | 0.71 | ESR2 (0.52) | KCNK3KCNK9NPC1RAB9A | |
| SCHEMBL6646273 | 0.69 | KCNK3 (0.43) | KMT2AKCNK3KCNK9NPC1RAB9A | |
| SCHEMBL6648070 | 0.67 | SMN1; SMN2 (0.44) | LMNASMN1; SMN2MEN1KMT2AKCNK3 | |
| SCHEMBL6645986 | 0.67 | SMN1; SMN2 (0.65) | LMNASMN1; SMN2MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040133008-A1 | Amide compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-07-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040133008-A1 | Amide compounds | APOB, APOL1, LDLR | NOD1 850/4885LMNA 1410/4885SMN1; SMN2 1836/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.