Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.71 |
| ▸ | CA9 | Q16790 | 2/20 | 0.62 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.61 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.61 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.61 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.61 |
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.56 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.56 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.56 |
| ▸ | FEN1 | P39748 | 1/20 | 0.56 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | NPEPPS | P55786 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15798127 | 0.78 | SMN1; SMN2 (0.53) | ALDH1A1CA9ADORA3ADORA1CYP1A2 | |
| SCHEMBL30293225 | 0.78 | SMN1; SMN2 (0.53) | ALDH1A1CA9ADORA3ADORA1CYP1A2 | |
| SCHEMBL430775 | 0.76 | ADORA3 (1.00) | ALDH1A1CA9ADORA3ADORA2AADORA2B | |
| SCHEMBL29897963 | 0.76 | ADORA3 (1.00) | ALDH1A1CA9ADORA3ADORA2AADORA2B | |
| SCHEMBL22251594 | 0.74 | ALDH1A1 (0.47) | ALDH1A1CA9ADORA3ADORA2AADORA2B | |
| SCHEMBL6668697 | 0.72 | CA9 (0.59) | ALDH1A1CA9CA12FEN1HPGD | |
| SCHEMBL22716785 | 0.72 | CYP1A2 (0.65) | ALDH1A1ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL31189218 | 0.72 | CYP1A2 (0.65) | ALDH1A1ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL1520708 | 0.72 | FEN1 (1.00) | ALDH1A1CA9ADORA3ADORA2AADORA2B | |
| SCHEMBL19577287 | 0.72 | ALDH1A1 (0.61) | ALDH1A1CA9ADORA3ADORA2AADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401830-A2 | QUINAZOLINEDIONES AS ANTIBACTERIAL AGENTS | Warner-Lambert Company LLC (US) | 2004-03-31 | — | — | EP | disclosed |
| US-20030114666-A1 | Having quinazolindione core structure; non-antibiotic resistance | WARNER-LAMBERT COMPANY | 2003-06-19 | — | — | US | disclosed |
| WO-2002102793-A2 | QUINAZOLINEDIONES AS ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY LLC (US) | 2002-12-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030114666-A1 | Having quinazolindione core structure; non-antibiotic resistance | ABCC1, RPS6KA1, SIGMAR1 | ALDH1A1 781/4885CA9 3346/4885ADORA3 2223/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.